Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery

Perioperative Administration of Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery

This is a placebo controlled randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery.

Inclusion Criteria:

• Patients must be 18 years or older as well as willing and able to provide informed consent
• Patients must be undergoing a scheduled surgery for pelvic organ prolapse or urinary incontinence
• Standard postoperative plan must include admission to the hospital with foley catheterization overnight the night after surgery, and planned removal of foley catheter and active voiding trial on postoperative day 1.

Exclusion Criteria:

• Patient unable or unwilling to provide informed consent
• Severe allergy to sulfa drugs
• Known allergy to tamsulosin or another alpha antagonist medication
• History of urinary retention
• Planned bladder catheterization greater than 24 hours after surgery
• Current use of alpha antagonist medication for hypertension
• End stage renal or liver disease