Upper Gastrointestinal Lesions in Crohn's Disease

Upper Gastrointestinal Lesions in Crohn's Disease: a Cross-sectional Cohort Study

A cross-sectional study was performed from 2017 to 2018. Consecutive Crohn's disease patients diagnosed in the Inflammatory bowel disease center of the Sixth Affiliated Hospital of Sun Yat-sen University were recruited. All patients underwent upper gastrointestinal endoscopy and biopsy by two defined endoscopists and two pathologists, the basic information were collected at the same time, in order to assess the prevalence of upper gastrointestinal involvement, and determine the role of upper gastrointestinal endoscopy in adult Crohn's disease patients, irrespective of upper gastrointestinal symptoms.

Inclusion Criteria:

• Age is 18 years old or older
• patients with diagnosis of Crohn's disease

Exclusion Criteria:

• diagnostic data were incomplete
• patients with malignant tumor
• use of PPIs or non-steroidal anti-inflammatory drugs in the preceding 4 weeks