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| Name | Class |
|---|---|
| Rockefeller University | OTHER |
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The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| prolonged overnight fasting | Experimental | Participants randomized to the fasting arm will be instructed on how to use the SMS texting app to indicate the beginning and end of the nightly fast. In the first 2-4 weeks following the first overnight fast, intervention participants will complete three phone calls with study staff trained in motivational interviewing. These calls will be used to reinforce the prolonged overnight fasting instructions, identify barriers to prolonged overnight fasting, and support successes where they have occurred. |
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| usual care | Active Comparator | Participants randomized to the usual care arm will be instructed to eat a heart-healthy diet and exercise for at least 30 minutes five days a week, which is usual counseling in our clinics. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| prolonged overnight fasting | Other | Three phone calls using motivational interviewing, support via SMS text. |
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| Measure | Description | Time Frame |
|---|---|---|
| Participation completion | Proportion of registered participants who successfully complete the 6-month intervention | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| measure of glucose metabolism | Assess the effect of prolonged overnight fasting on glucose metabolism, measured by glycosylated hemoglobin (HbA1c). | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Danielle Friedman, MD, MS | Memorial Sloan Kettering Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States |
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| Label | URL |
|---|---|
| Memorial Sloan Kettering Cancer Center | View source |
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| ID | Term |
|---|---|
| D005215 | Fasting |
| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| D001519 | Behavior |
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The OnFACT study is a pilot randomized controlled trial of prolonged overnight fasting among adult survivors of childhood cancer.
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| usual care | Other | Eat a heart-healthy diet and exercise for at least 30 minutes five days a week |
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