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| Name | Class |
|---|---|
| University Hospital Plymouth NHS Trust | OTHER |
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This is a study comparing routine inclusion of the lower neck in initial CT thorax in patients with suspected lung cancer to not including it. The study aims to assess whether such an intervention reduces the number of invasive investigations required to achieve a final diagnosis and clinical stage and whether it improves the detection of cervical lymph nodes involvement by lung cancer.
Two practices currently exist regarding the role of lower neck CT in patients with suspected lung cancer but with little evidence for either. Routine lower neck CT is potentially associated with benefits of higher detection of neck lymphadenopathy leading to better staging, less invasive procedure with positive implications for patients experience and care. The potential harms are delay in diagnosis due to false positive findings and radiation exposure. There is limited evidence in this area so this study will potentially provide evidence to inform health policy decisions based on the risk benefit balance.
This is a retrospective comparative study to assess the real-life impact of routine lower neck CT on the diagnostic and staging work up of patients with suspected lung cancer across two cohorts.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No neck CT | Cohort of patients with suspected lung cancer where the lower neck is not routinely included in CT |
| |
| Neck CT | Cohort of patients with suspected lung cancer where the lower neck is routinely included in CT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| lower neck CT | Diagnostic Test | Computerised tomography of the lower neck done as part of initial CT thorax and lower abdomen |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of pathologically confirmed malignant supraclavicular lymph node | evidence of malignancy consistent with lung cancer on fine needle aspiration or core biopsy | 60 days from initial CT |
| Measure | Description | Time Frame |
|---|---|---|
| Number of diagnostic procedures performed per patient | number of invasive procedures used to obtain tissue to achieve diagnosis and/or stage | 60 days from initial CT Thorax |
| Proportion of patients who underwent more than one diagnostic procedures |
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Inclusion Criteria:
Exclusion Criteria:
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Patients initially seen with suspected lung cancer
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mohammed Ahmed, Dr | Contact | 0035391524222 | jamaleldeen@gmail.com |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| 60 days from initial CT Thorax |
| Proportion of patients who underwent Endobronchial Ultrasound (EBUS) | 60 days from initial CT Thorax |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |