Comparing Radiological Tubal Blockage Versus Laparoscopic Salpingectomy in Infertile Women With Hydrosalpinx During in Vitro Fertilization Treatment

A Randomized Trial Comparing Radiological Tubal Blockage Versus Laparoscopic Salpingectomy in Infertile Women With Hydrosalpinx During in Vitro Fertilization Treatment

Hydrosalpinx (HX) has a detrimental effect on the rates of implantation, pregnancy, live delivery, and early pregnancy loss during in vitro fertilization (IVF). The effectiveness of radiological tubal blockage has not been compared with the standard treatment of laparoscopic salpingectomy in randomized trials. The investigators aim in this randomized trial to compare the live birth rate of radiological tubal blockage versus laparoscopic salpingectomy in infertility women with HX prior to frozen-thawed embryo transfer (FET). Eligible women will be recruited and randomized into one of the following two groups: (1) the radiological tubal blockage group and (2) the laparoscopic salpingectomy group. The primary outcome is the live birth rate.

Inclusion Criteria:

• Women aged 20-43 years at the time of IVF/ICSI treatment
• Unilateral or bilateral HX visible on pelvic ultrasound or hysterosalpingogram
• At least one frozen embryo or blastocyst available for transfer

Exclusion Criteria:

• A history of pelvic inflammatory disease within 6 months
• HX that were already blocked proximally on hysterosalpingogram
• Frozen pelvis from previous laparoscopy
• Women with fibroids interfering with radiological tubal blockage
• Undergoing preimplantation genetic testing