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Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation. In addition to substantial weight loss, emerging studies have highlighted that metabolic surgery can substantially ameliorate obesity-related metabolic diseases, including but not limited to type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea-hypopnea syndrome (OSAHS) and polycystic ovary syndrome (PCOS)in severely obese patients. However, further investigations with larger sample size and longer observation time still needed to clarity the efficacy and safety of metabolic surgery in Chinese patients with obesity and encouraging future research in this field.
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| Measure | Description | Time Frame |
|---|---|---|
| the excess weight loss effect of metabolic surgery after 1year | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2) | 1 year after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| the adverse events rate of metabolic surgery | show the surgical safety by 30 days follow-up according to guideline（such as: bleeding, leak, obstruction, re-operation for complication） | 30 days after surgery |
| the excess weight loss effect of metabolic surgery with long-time follow-ups |
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Inclusion Criteria:
Exclusion Criteria:
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patients with morbid obesity who are suitable and willing to accept metabolic surgical procedure and also agree with the registry
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhongtao Zhang, M.D. | Contact | +86-13801060364 | zhangzht@ccmu.edu.cn | |
| Mengyi Li, M.D. | Contact | +86-15810993198 | muzi_1990@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Zhongtao Zhang, M.D. | Beijing Friendship Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing Friendship Hospital | Recruiting | Beijing | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32483745 | Derived | Lv H, Li M, Liu Y, Zhao L, Sun J, Cao D, Zeng N, Liu J, Liu Y, Bian S, Zhang P, Yang Z, Zhang Z, Wang Z. The Clinical Value and Appropriateness Criteria of Upper Abdominal Magnetic Resonance Examinations in Patients Before and After Bariatric Surgery: a Study of 837 Images. Obes Surg. 2020 Oct;30(10):3784-3791. doi: 10.1007/s11695-020-04688-w. | |
| 30653786 |
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
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Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2) |
| 3 years |
| the excess weight loss effect of metabolic surgery with long-time follow-ups | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2) | 5 years |
| the excess weight loss effect of metabolic surgery with long-time follow-ups | Percent excess weight loss (%EWL), %EWL=[(initial weight)-(post-op weight)]/[(initial weight)-(ideal weight)] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2) | 10 years |
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 3 years |
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 5 years |
| the glycemic control effect of metabolic surgery with long-time follow-ups | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 10 years |
| the glycemic control effect of metabolic surgery after 1 year | the decrease of HbA1c, glucose level, C-peptide and insulin levels | 1 year after surgery |
| Zhang P, Liu Y, Lv H, Li MY, Yu FX, Wang Z, Ding HY, Wang LX, Zhao KX, Zhang ZY, Zhao PF, Li J, Yang ZH, Zhang ZT, Wang ZC. Integration of Neural Reward Processing and Appetite-Related Signaling in Obese Females: Evidence From Resting-State fMRI. J Magn Reson Imaging. 2019 Aug;50(2):541-551. doi: 10.1002/jmri.26576. Epub 2019 Jan 17. |