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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A01498-37 | Other Identifier | ID-RCB number, ANSM |
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Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats. The present project aims at investigating such attentional bias in patients with PTSD using the change blindness paradigm that offers the interesting possibility of studying sensitivity to sudden changes using ecological stimuli. More precisely, the investigators will investigate whether patients are more sensitive than matched controls to sudden changes in the visual environment and whether this hypersensitivity is specific or even stronger when visual information has an emotional content. The attentional bias will be measured using motor responses (accuracy and speed to indicate the occurrence of a change by pressing a button) as well as eye movements.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Post-Traumatic Stress Disorders (PTSD) | 30 patients with PTSD (diagnosis based on the standard DSM criteria) | ||
| Controls | 30 healthy controls without any psychiatric or neurological diagnosis |
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| Measure | Description | Time Frame |
|---|---|---|
| Response time before the detection of neutral and emotional stimuli. | The explicit response of the participants will be measured with the response time before the detection of neutral and emotional stimuli. | Baseline: one session |
| Measure | Description | Time Frame |
|---|---|---|
| Number of correct detections compared with the missed detections and false alarms. | Performances will be measured by a sensitivity index (D prime) . This sensitivity index considers the number of correct detections compared with the missed detections and false alarms. | Baseline: one session |
| Total duration until the participant first fixed on a ROI. |
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Inclusion Criteria:
Exclusion Criteria:
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Thirty patients with PTSD and 30 participants exposed to trauma without PTSD will be asked to detect neutral or emotional changes in 96 scenes.
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| Name | Affiliation | Role |
|---|---|---|
| Guillaume VAIVA | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital, Lille | Lille | 59037 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39314214 | Result | Creupelandt C, Veerapa E, Bugnet A, Wathelet M, Demesmaeker A, Grandgenevre P, Vaiva G, Fovet T, D'Hondt F. Comment on: Attentional bias modification and attention control training in PTSD: a systematic review and meta-analysis. Ther Adv Psychopharmacol. 2024 Sep 17;14:20451253241278872. doi: 10.1177/20451253241278872. eCollection 2024. No abstract available. | |
| 36259422 |
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| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
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The implicit response will be measured by the localization and duration of fixations. All fixations outside the recording field will be excluded. The main variable will be the mean latency of the first fixation in a region of interest (ROI). This variable corresponds to the total duration until the participant first fixed on a ROI. |
| Baseline: one session |
| Veerapa E, Grandgenevre P, Vaiva G, Duhem S, Fayoumi ME, Vinnac B, Szaffarczyk S, Wathelet M, Fovet T, D'Hondt F. Attentional bias toward negative stimuli in PTSD: an eye-tracking study. Psychol Med. 2023 Sep;53(12):5809-5817. doi: 10.1017/S0033291722003063. Epub 2022 Oct 19. |
| 32678129 | Result | Veerapa E, Grandgenevre P, El Fayoumi M, Vinnac B, Haelewyn O, Szaffarczyk S, Vaiva G, D'Hondt F. Attentional bias towards negative stimuli in healthy individuals and the effects of trait anxiety. Sci Rep. 2020 Jul 16;10(1):11826. doi: 10.1038/s41598-020-68490-5. |