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Does the presence of intracavitary fluid during hormonal stimulation for IVF depends on the position of C-section-scar ?
To evaluate the correlation between the presence of intracavitary fluid and the position of the C-section-scar in relation to the uterine fundus and the inner cervical os.
To this end, we will compare measured variables, in patients with intracavitary fluid and without intracavitary fluid.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with intracavitary fluid | to evaluate the correlation between the presence of intracavitary fluid during hormonal stimulation for IVF depending on the position of C-section-scar and the presence of an isthmocele, this group patients will have intracavitary fluid. |
| |
| Patients without intracavitary fluid | to evaluate the correlation between the presence of intracavitary fluid during hormonal stimulation for IVF depending on the position of C-section-scar and the presence of an isthmocele, in this group patients will not have intracavitary fluid. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ultrasound,transvaginal scan | Diagnostic Test | The presence of fluid in the uterine cavity during hormonal stimulation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Presence/Absence of ICF | to evaluate the correlation between the presence of intracavitary fluid and the position of the C-section-scar in relation to the inner cervical os, during hormonal stimulation for IVF. | 1 year and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Thickness of fluid accumulation in the cavity | Presence or Absence of ICF | 1 year and 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing IVF treatment in the IVI Middle East Clinic Abu Dhabi and Dubai, due to secondary infertility and delivery with at least one previous C-section.
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| Name | Affiliation | Role |
|---|---|---|
| Human Fatemi, MD | ART Fertility Clinics LLC | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IVI Middle East Fertility Clinic | Abu Dhabi | 60202 | United Arab Emirates |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21031351 | Background | Bij de Vaate AJ, Brolmann HA, van der Voet LF, van der Slikke JW, Veersema S, Huirne JA. Ultrasound evaluation of the Cesarean scar: relation between a niche and postmenstrual spotting. Ultrasound Obstet Gynecol. 2011 Jan;37(1):93-9. doi: 10.1002/uog.8864. | |
| 23680518 | Background | Tower AM, Frishman GN. Cesarean scar defects: an underrecognized cause of abnormal uterine bleeding and other gynecologic complications. J Minim Invasive Gynecol. 2013 Sep-Oct;20(5):562-72. doi: 10.1016/j.jmig.2013.03.008. Epub 2013 May 14. |
| Label | URL |
|---|---|
| Rise in number of C-section deliveries. | View source |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| 26409016 | Background | Vervoort AJ, Uittenbogaard LB, Hehenkamp WJ, Brolmann HA, Mol BW, Huirne JA. Why do niches develop in Caesarean uterine scars? Hypotheses on the aetiology of niche development. Hum Reprod. 2015 Dec;30(12):2695-702. doi: 10.1093/humrep/dev240. Epub 2015 Sep 25. |
| 11821277 | Background | Chien LW, Au HK, Xiao J, Tzeng CR. Fluid accumulation within the uterine cavity reduces pregnancy rates in women undergoing IVF. Hum Reprod. 2002 Feb;17(2):351-6. doi: 10.1093/humrep/17.2.351. |
| 31885047 | Derived | Lawrenz B, Melado L, Garrido N, Coughlan C, Markova D, Fatemi H. Isthmocele and ovarian stimulation for IVF: considerations for a reproductive medicine specialist. Hum Reprod. 2020 Jan 1;35(1):89-99. doi: 10.1093/humrep/dez241. |