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| Name | Class |
|---|---|
| Liuzhou Maternity and Child Healthcare Hospital | OTHER |
| Qingdao Municipal Hospital | OTHER |
| Zhongshan People's Hospital, Guangdong, China | OTHER |
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This study aims to investigate the status of pelvic floor function of healthy female in China, including premenopausal nullipara, premenopausal women with childbirth and postmenopausal women.
This is a cross-sectional survey. The normal physical examination population is divided into three groups,including premenopausal nullipara, premenopausal women with childbirth and postmenopausal women. The pelvic floor muscle function in three groups are evaluated. The modified Oxford Grading Scale and Levator ani testing is used to quantify PFM strength through vaginal palpation. Pelvic floor muscle strength ,endurance, repetition,vaginal contraction pressure and the knack test are evaluated using a PHENIX USB 8 neuromuscular stimulation therapy system (Company: Vivaltis-Electronic Concept Lignon Innovation, Montpellier, France). In six different regions of China according to geographic region (northwest, southwest, north, east, northeast, and central-south China) , 1 or more hospitals in each area are selected as sub-centers, which needs to complete the evaluation of pelvic floor muscle function of 360 cases in 3 groups totally.
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| Measure | Description | Time Frame |
|---|---|---|
| maximum vaginal contraction pressure | it is measured by manometry, range(80-150cmH2O). The higher values represent better outcomes. | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| Pelvic floor muscle strength | The modified Oxford Grading Scale is used to quantify PFM strength through vaginal palpation. range(0-5).The higher values represent better outcomes. through vaginal palpation. | 1 day |
| Pelvic floor muscle strength(repetition) |
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Inclusion Criteria:
Group A:Premenopausal women without history of abortion or delivery
Group B:Premenopausal women with childbirth
Group C:Postmenopausal women (over a year, except surgical menopause)
Exclusion Criteria:
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Volunteers are divided into three groups, and each clinical center requires at least 120 persons in each group.
Group A: Premenopausal women without history of abortion or delivery.
Group B: Premenopausal women with childbirth (including cesarean section or natural birth).
Group C:Postmenopausal women (except surgical menopause).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhijing Sun, MD | Contact | 13651314354 | sunzhj2001@sina.com | |
| Lan Zhu, MD | Contact | zhu_julie@vip.sina.com |
| Name | Affiliation | Role |
|---|---|---|
| Lan Zhu, MD | Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences | Recruiting | Beijing | Beiing | 100730 | China |
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| The First Affiliated Hospital with Nanjing Medical University |
| OTHER |
| Second Affiliated Hospital of Soochow University | OTHER |
| Maternity and Child Health Hospital of Changsha | UNKNOWN |
| Henan Provincial People's Hospital | OTHER |
| Huaian Maternal and Child Health Care Hospital | OTHER |
| Hunan Provincial Maternal and Child Health Care Hospital | OTHER |
| The Fourth Hospital of Shijiazhuang | OTHER |
| Shenzhen Luohu District Maternity And Child Healthcare Hospital | OTHER |
| Second Affiliated Hospital of Wenzhou Medical University | OTHER |
| Hubei Shiyan People's Hospital | UNKNOWN |
| Changzhi Maternity & Child Health Hospital | OTHER |
| Maternal and Child Health Care Hospital of Xinjiang Uygur Autonomous Region | UNKNOWN |
| The First Hospital of Hebei Medical University | OTHER |
| Shen-Zhen City Maternity and Child Healthcare Hospital | OTHER |
| Dalian Medical University | OTHER |
| Maternity and Child Care Center of QinHuangDao City | UNKNOWN |
| The People's Hospital of Leshan | OTHER |
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Levator ani testing is used to quantify PFM strength. range(0-5). The higher values represent better outcomes. |
| 1 day |
| Pelvic floor muscle contraction endurance | muscle contractions maintained for 0 s are defined as grade 0, 1 s as grade I, 2 s as grade II, 3 s as grade III, 4 s as grade IV, and 5 s or longer as grade V. Normal muscles can maintain the contraction for 5 s. range(0-5s). The higher values represent better outcomes. | 1 day |
| pelvic organ prolapse quantification | POP-Q is measured when maximum valsalva. range(0-4). stage 0 represents normal. | 1 day |
| the knack test | a voluntary PFM contraction before or during coughing. That the contraction could be performed represents normal. | 1 day |
| vaginal rest pressure | measure when no vaginal contraction by manometry. range(25-50 cmH2O). the lower and the higher values represent abnormal outcomes. | 1 day |