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No participants enrolled
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This is a randomized prospective study that will compare the use of narcotics in a control group of non-injected patients with a treatment arm of patients injected intra-operatively with a ropivacaine, morphine, and epinephrine cocktail. The investigators hypothesize that this treatment will reduce narcotic use in patients during their hospital stay, and possibly decrease the length of their stay in the hospital.The investigators also hope their pain will be decreased as displayed by their multi-daily Clinically Aligned Pain Assessment (CAPA) score.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lumbar Spine Surgery with Injection | Experimental | Patients undergoing lumbar spine surgery will receive a peri-incisional injection of pain medications (morphine, epinephrine, and ropivacaine) during their surgery. |
|
| Lumbar Spine Surgery without Injection | No Intervention | Patients undergoing lumbar spine surgery will NOT receive a peri-incisional injection of pain medications during their surgery. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Morphine | Drug | Morphine, epinephrine, and ropivacaine cocktail will be administered peri-incisionally during lumbar spine surgery. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post-operative narcotic use | Up to 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Patients' self-reported pain (CAPA) scores | Evaluates
| Up to 6 weeks |
| Length of hospital stay |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 | United States |
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| ID | Term |
|---|---|
| D007405 | Intervertebral Disc Displacement |
| D055959 | Intervertebral Disc Degeneration |
| D013168 | Spondylolisthesis |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D006547 | Hernia |
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| ID | Term |
|---|---|
| D009020 | Morphine |
| D004837 | Epinephrine |
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D009022 | Morphine Derivatives |
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
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This is a single blind study in which participants are unaware of whether or not they received a peri-incisional injection of pain medication during their surgery.
| Epinephrine | Drug | Morphine, epinephrine, and ropivacaine cocktail will be administered peri-incisionally during lumbar spine surgery. |
|
| naropin | Drug | Morphine, epinephrine, and ropivacaine cocktail will be administered peri-incisionally during lumbar spine surgery. |
|
| Up to 6 weeks |
| D020763 |
| Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013169 | Spondylolysis |
| D055009 | Spondylosis |
| D006571 |
| Heterocyclic Compounds |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |
| D004983 | Ethanolamines |
| D000605 | Amino Alcohols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
| D000588 | Amines |
| D015306 | Biogenic Monoamines |
| D001679 | Biogenic Amines |
| D002395 | Catecholamines |
| D002396 | Catechols |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |