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Lack of funding.
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The investigators theorize that the application of a lidocaine-prilocaine cream 5-10 minutes prior to the administration of a paracervical block could decrease pain associated with its administration and pain with abortion overall.
This is a superiority, double-blind randomized controlled trail of women ages 18 and older presenting for first-trimester surgical abortion. The lidocaine-prilocaine cream will be used in the experimental group in conjunction with a paracervical block, whereas plain lubricating gel will be used in conjunction with a paracervical block for the placebo, control group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lidocaine-prilocaine cream | Experimental | 5-10 minutes prior to the start of the procedure, the participant will self-administer 10ml of the lidocaine-prilocaine cream vaginally using a syringe |
|
| Placebo cream (pain lucubrating gel) | Placebo Comparator | 5-10 minutes prior to the start of the procedure, the participant will self-administer 10ml of the placebo cream vaginally using a syringe |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lidocaine-Prilocaine Cream | Drug | 10ml of vaginally self-administered cream composed of an eutectic mixture of 2.5% lidocaine, 2.5% prilocaine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain perceived as measured by a Visual Analog Scale (0-100mm) at the time of cervical dilation | Intraoperative; Immediately following cervical dilation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Principal Investigator | Stanford University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford Health Care | Stanford | California | 94305 | United States |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010468 | Perceptual Disorders |
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|
| Placebo Cream | Drug | 10ml of vaginally self-administered placebo cream |
|
| 1% Lidocaine Paracervical Block | Drug | Paracervical block of 10ml of 1% lidocaine |
|
| D019954 | Neurobehavioral Manifestations |
| D009422 | Nervous System Diseases |