To focus on the real world treat-to-target rate of early rheumatoid arthritis patients who will be treated according to the 2015 American College of Rheumatology Guideline for the Treatment of RA.

To explore the factors which influence the treat-to-target outcome.

Resent study showed that rapid progression of cartilage and bone damage could happen on the early state of RA patients, so the clinicians should try the best to stop the trend, such as early diagnosis, early treatment and treat-to-target. But only half of the RA patients could reach low disease activity in the whole world and about 10% in China.

The investigators enroll early RA patients who are treated according to the 2015 American College of Rheumatology Guideline. The relevant data are collected and analyzed by the statistician including clinical data, imaging markers, blood samples and patient-reported outcomes every 3 months.

Inclusion Criteria:

• ≥18 years,
• be diagnosed with RA according to the 1987 or 2010 ACR criteria,
• in the course of the disease within 6 months,
• fill out questionnaires by oneself,
• fully understand the survey, agree to take part in the survey with signing the informed consent, and authority the researchers to expose and use his or her personal health information.

Exclusion Criteria:

• woman in pregnancy, lactation or plan to pregnant in the next 2 years,
• before enter this study, the patient joint any other RA clinical study in the past 24 weeks,
• according to the clinicians, one may not report his /or her life quality or the utilization of leading medical resources.

Participants entering this study are recruited from two hospital sites: Nanfang Hospital, Southern Medical University and Zhujiang Hospital, Southern Medical University.