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Objective: To evaluate the effects of an early-based cardiac rehabilitation program on the functional capacity, inspiratory muscular strength and clinical outcomes in hospitalized heart failure patients before and after heart transplantation. Method: 30 hospitalized heart failure patients awaiting cardiac transplantation will be selected and randomized in 2 groups: conventional group (n = 15) - conventional exercise protocol: breathing exercises and global active exercises of upper and lower limbs in the sitting position; and Intervention group (n = 15) - cycle ergometer exercise protocol: each session consists of cycling on a stationary bicycle in the seated position for 20 minutes. In both groups, the exercise protocols will be applied twice a day until the hospital discharge, always supervised by a physiotherapist and a doctor. The evaluation procedures in all patients of the research will be: functional capacity measured by the 6 minute walk test and inspiratory muscle strength measured by manovacuometry. Evaluations will be repeated in 3 distinct moments: after 24h of hospital admission and/or clinical stabilization; before transplantation and after transplantation in hospital discharge.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Conventional exercise protocol | Experimental | Conventional global exercise |
|
| Cycle ergometer exercise protocol | Experimental | Stationary cycle ergometer exercise |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Conventional exercise protocol | Other | Breathing exercises and global active exercises of the upper and lower limbs while in the upright seated position |
|
| Measure | Description | Time Frame |
|---|---|---|
| Six-minute walk test to measure functional capacity change | According to the baseline distance walked, we will evaluate the improvement in functional capacity after the period of the rehabilitation programs | After 24 hours of hospital admission or clinical stabilization; before transplantation (after 4 weeks of rehabilitation program) and in hospital discharge (after 4 weeks of transplantation). |
| Respiratory muscle strength | By manovacuometry, assessing the change in inspiratory muscle pressure and expiratory muscle pressure | After 24 hours of hospital admission or clinical stabilization; before transplantation (after 4 weeks of rehabilitation program) and in hospital discharge (after 4 weeks of transplantation) |
| Measure | Description | Time Frame |
|---|---|---|
| Invasive mechanical ventilation | Duration of invasive mechanical ventilation will be recorded after cardiac transplantation. | First day after transplantation. |
| Duration of intensive care unit stay |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Caroline Barbosa | Contact | 5511 953578342 | carolinebublitz@yahoo.com.br |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Caroline Bublitz Barbosa | Recruiting | São Paulo | 04024002 | Brazil |
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| Cycle ergometer exercise protocol | Other | Stationary cycle ergometer exercise while in the upright seated position for 20 minutes. The protocol will be performed intermittently with 5 periods; each period consists of 3 minutes of cycling followed by 1-minute of rest. |
|
Duration of stay in intensive care unit (in days) after transplantation will be recorded.
| In hospital discharge (after 4 weeks of transplantation). |
| Hospitalization stay | Duration of stay in the hospital (in days) will be recorded. | In hospital discharge (after 4 weeks of transplantation). |
| ID | Term |
|---|---|
| D006333 | Heart Failure |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001519 | Behavior |
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