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Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc. In this clinical trial, the investigators aim to analyze the effect of nanofat grafting on treating androgenic alopecia in male.
The investigators will treat the hair loss area of a patient by processed nanofat grafting. The participants were asked to come back 1、3、6、9、12 months after treatment for further follow-up.
Before and after the treatment, the hair and follicular will be assessed subjectively by satisfaction assessment, dermatoscope.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| processed Nanofat grafting | Experimental | processed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nanofat grafting | Procedure | hair loss area will be treated by processed autologous Nanofat grafting |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dermatoscope | the density of hair follicle and diameter of hair will be analized by dermatoscope before and after the treatment of Nanofat grafting. | Baseline and at1,3,6,9,12 months after the treatment |
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| Measure | Description | Time Frame |
|---|---|---|
| Satisfaction assessments | the satisfaction will be assessed after the treatment | 1,3,6,12 months after treatment |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the first affiliated hospital of Jinan University | Guangzhou | Guangdong | 510000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23783059 | Background | Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H. Nanofat grafting: basic research and clinical applications. Plast Reconstr Surg. 2013 Oct;132(4):1017-1026. doi: 10.1097/PRS.0b013e31829fe1b0. | |
| 28875863 | Background | Won CH, Park GH, Wu X, Tran TN, Park KY, Park BS, Kim DY, Kwon O, Kim KH. The Basic Mechanism of Hair Growth Stimulation by Adipose-derived Stem Cells and Their Secretory Factors. Curr Stem Cell Res Ther. 2017;12(7):535-543. doi: 10.2174/1574888X12666170829161058. |
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| ID | Term |
|---|---|
| D000505 | Alopecia |
| D034062 | Insomnia, Fatal Familial |
| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| 28975248 | Background | Gu Z, Li Y, Li H. Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars. JAMA Facial Plast Surg. 2018 Mar 1;20(2):128-135. doi: 10.1001/jamafacial.2017.1329. |
| D020763 |
| Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D017096 | Prion Diseases |
| D002494 | Central Nervous System Infections |
| D007239 | Infections |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019636 | Neurodegenerative Diseases |
| D007319 | Sleep Initiation and Maintenance Disorders |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |