A Study of Lanabecestat in Healthy Female Participants Taking Oral Contraceptive

Effect of Lanabecestat on the Pharmacokinetics of Ethinyl Estradiol and Levonorgestrel in Healthy Female Subjects

The study will evaluate the effect of oral contraceptive (birth control pill) on the blood level of lanabecestat when both are given together. Side effects will be monitored and documented. This study will last up to 27 days for each participant, not including screening. Screening is required within 42 days prior to first dose.

Inclusion Criteria:

• Are healthy female participants
• Women not of childbearing potential; women of childbearing potential using a non-hormonal intrauterine device (IUD)
• Have a body mass index (BMI) of 17.5 to 32 kilogram per meter square (kg/m²)

Exclusion Criteria:

• Have a history of or current significant ophthalmic disease, which includes participants with clinically significant eye abnormalities, particularly any eye problem involving the retina, as determined by the investigator
• Have vitiligo or any other clinically significant disorder of skin or hair pigmentation, as determined by the investigator
• Have a history of or current neuropsychiatric disease/condition including psychosis, affective disorder, anxiety disorder, borderline state, or personality disorder