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Pneumonia is a major cause of ICU admission, or may complicate ICU course. Among the causative pathogens, Stenotrophomonas Maltophilia is a rare pathogen, but affects usually patients with chronic pulmonary co-morbidities, or with long duration of mechanical ventilation and multiples treatment with broad spectrum antimicrobial therapy. However, there are only a paucity of data regarding epidemiology, impact and outcome of Pneumonia due to Stenotrophomonas Maltophilia in critically ill patients.
Primary objective was to study factors associated with mortality in case of Pneumonia due to Stenotrophomonas Maltophilia. Secondary objectives were to describe factors associated with morbidity of Pneumonia due to Stenotrophomonas Maltophilia (duration of mechanical ventilation, ICU length of stay), and to report the characteristics of critically ill patients presenting Pneumonia due to Stenotrophomonas Maltophilia.
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| Measure | Description | Time Frame |
|---|---|---|
| Treatment failure | Treatment failure is defined as composite of death and recurrence of pneumonia due to Stenotrophomonas Maltophilia within 30 days of the first episode | Day 30 |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of mechanical ventilation | Number of days under mechanical ventilation | Day 30 |
| Recurrence of pneumonia due to Stenotrophomonas Maltophilia | New onset of pneumonia due to Stenotrophomonas Maltophilia |
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Inclusion Criteria:
Patients older than 18 years
Documented Stenotrophomonas maltophilia pneumonia:
Exclusion Criteria:
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Patients hospitalized in Intensive Care Unit and presenting pneumonia due to Stenotrophomonas maltophilia
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| Name | Affiliation | Role |
|---|---|---|
| Adrien Bouglé, MD | APHP | Study Director |
| Philippe Guerci, MD | CHRU NANCY | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Réanimation Polyvalente CHR Metz-Thionville | Metz | France | ||||
| Department of Anesthesiology and Critical Care Medicine, University Hospital of NANCY |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31752976 | Derived | Guerci P, Bellut H, Mokhtari M, Gaudefroy J, Mongardon N, Charpentier C, Louis G, Tashk P, Dubost C, Ledochowski S, Kimmoun A, Godet T, Pottecher J, Lalot JM, Novy E, Hajage D, Bougle A; AZUREA research network. Outcomes of Stenotrophomonas maltophilia hospital-acquired pneumonia in intensive care unit: a nationwide retrospective study. Crit Care. 2019 Nov 21;23(1):371. doi: 10.1186/s13054-019-2649-5. |
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| ID | Term |
|---|---|
| D053717 | Pneumonia, Ventilator-Associated |
| D016638 | Critical Illness |
| D018410 | Pneumonia, Bacterial |
| D011014 | Pneumonia |
| ID | Term |
|---|---|
| D000077299 | Healthcare-Associated Pneumonia |
| D003428 | Cross Infection |
| D007239 | Infections |
| D012141 | Respiratory Tract Infections |
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| Day 30 |
| Mortality | Day 30 |
| Nancy |
| 54500 |
| France |
| Department of Anesthesiology and Critical Care Medicine, University Hospital of Strasbourg | Strasbourg | France |
| Anesthesiology and Critical Care Medicine, Groupe Hospitalier Pitié-Salpêtrière | Paris | Île-de-France Region | 75013 | France |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D007049 | Iatrogenic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |