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Develop a new scoring system for HCC patients with tumor rupture.
There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Analysis before liver resection | Multivariate analysis of predictive factors associated with survival |
| |
| Different risk group | Low-risk group, moderate-risk group, high-risk group |
| |
| Model comparison | Comparison of models in predicting survival |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liver resection | Procedure | Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | Overall survival after partial hepatectomy | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Disease-free survival | Recurrence-free survival after partial hepatectomy | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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Ten year HCC rupture patients who received partial hepatectomy at Tongji Hospital of the Huazhong University of Science and Technology
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| Name | Affiliation | Role |
|---|---|---|
| Bi-xiang Zhang, Prof, PHD | Huazhong University of Science and Technology | Study Chair |
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| ID | Term |
|---|---|
| D012422 | Rupture, Spontaneous |
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
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| ID | Term |
|---|---|
| D006498 | Hepatectomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |