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This study evaluates the overtreatment and deintensification rates of antidiabetic and antihypertensive medications in patients with diabetes mellitus in Turkey.
Diabetes mellitus is one of the most common chronic diseases which lead to serious public health problems and a significant economic burden worldwide. The prevalence of diabetes in elderly patients is very high and is predicted to increase dramatically.
Prior studies have generally been concerned with the inadequate treatment of diabetes however, over the last few years the overtreatment of diabetes has also come to the fore. Unfortunately, there are very few data worldwide and no data in Turkey about the overtreatment of patients with type 2 diabetes.
This study aimed to assess the rates and predictors of overtreatment and undertreatment of glycemia and blood pressure in older adults with T2DM. Treatment deintensification or intensification by the physicians were also investigated.
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| Measure | Description | Time Frame |
|---|---|---|
| Overtreatment for glycemia | HbA1c<6.5% plus use of ≥2 oral hypoglycemics or insulin, except metformine. | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Undertreatment for glycemia | HbA1c>9% | 7 days |
| Overtreatment for blood pressure | systolic blood pressure < 120 mmHg or diastolic blood pressure < 65 mmHg and use of at least one drug additional to ACE inhibitors |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 65 years and older and with type 1 or type 2 diabetes who were under follow-up in the same tertiary endocrine unit for at least a year were enrolled.
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| Name | Affiliation | Role |
|---|---|---|
| Alper Sonmez, Prof.Dr. | Gulhane School of Medicine, Endocrinology and Metabolism | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gulhane School of Medicine | Ankara | 06018 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| 7 days |
| Undertreatment for blood pressure | SBP≥140 mmHg or DPB ≥ 90 mmHg and use of two or less drugs | 7 days |
| Deintensification of treatment | discontinuation or dosage decrease within 6 months after the index measurement. | 7 days |