LLETZ Under General Versus Local Anesthesia

Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.

The investigators conduct a prospective, randomized trial to assess the benefits of performing large loop excision of the transformatione zone (LLETZ) under local anesthesia and compare it to LLETZ under general anesthesia. The primary endpoint of this study is women´s satisfaction.

Inclusion Criteria:

• colposcopy Prior to conization
• informed consent
• histologically proven high grade cervical dysplasia
• Transformation zone typ 1 or 2

Exclusion Criteria:

• significant language barrier
• a personal history of conization
• pregnancy
• the use of blood thinner
• unwillingness to participate
• oncological disease
• inpatient treatment
• women who are not fasting
• risk of aspiration
• columnar-squamous epithelium border not fully visible