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Attention deficit disorder in adults with or without hyperactivity (ADHD) is a common disorder, affecting around 3% of the population. ADHD increases the risk of psychiatric disorders (mood disorders, sleep disorders, personality disorders, addictive behavior), risky behaviors, and vocational difficulties. Emotional dysregulation (ED) constitute a major hindrance in the daily life of subjects, with a great impact on the general functioning and the quality of life of the patients.
The investigators want to determine the characteristics of patients with each type of ED (impulsivity, exacerbated emotional intensity, cyclothymia, borderline personality traits), and study the stability of these traits over time. Since circadian rhythms influence mood and circadian rhythms frequently occur in patients with ADHD, the investigators want to determine if there is a link between ED and instability in circadian rhythms. Finally, they would like to observe whether the ED evolves and according to whether or not treatment is taken
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort group | Experimental | All participants will have evaluations at inclusion and 12 months. Neuropsychological testing Actimetry Selfquestionnaires on emotional topics |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Neuropsychological testing | Other | The assessment will will be done at the time of the initial evaluation (undiagnosed / untreated patients), then at one year of follow-up |
|
| Measure | Description | Time Frame |
|---|---|---|
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of cyclothymia (TEMPS-A scale) | At inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of cyclothymia (TEMPS-A scale) | At 12 months after inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of emotional lability (ALS scale) | At inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of emotional lability (ALS scale) | At 12 months after inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of emotional dysregulation (WRAADDS scale) | At inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of emotional dysregulation (WRAADDS scale) | At 12 months after inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) |
| Measure | Description | Time Frame |
|---|---|---|
| Association between emotional dysregulation, cognitive deficits and circadian instability | Correlation between emotional dysregulation and executive and attentional dysfunction measured with the TAP test. Correlation between emotional dysregulation and instability index of circadian rhythms measured by actimetry. | At inclusion |
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Inclusion criteria:
Exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sébastien WEIBEL, MD | Hôpitaux Universitaires de Strasbourg | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Spécialisé de Rouffach - Secteur 8 | Rouffach | 68250 | France | |||
| Hôpitaux Universitaires de Strasbourg - Service de Psyhciatrie 2/PPSAM |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41803808 | Derived | Walter A, Martz E, Weiner L, Comtet H, Glacet R, Kilic-Huck U, Bourgin P, Schroder CM, Weibel S. Sleep, rest-activity rhythm, cognitive and emotional symptoms in adult ADHD: unraveling the links with an actimetry-based approach. BMC Psychiatry. 2026 Mar 9;26(1):317. doi: 10.1186/s12888-026-07947-9. |
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| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D009483 | Neuropsychological Tests |
| ID | Term |
|---|---|
| D011581 | Psychological Tests |
| D004191 | Behavioral Disciplines and Activities |
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|
| Actimetry | Other | The assessment will will be done at the time of the initial evaluation (undiagnosed / untreated patients), then at one year of follow-up. |
|
|
| Self-questionnaires on emotional topics | Other | The assessment will will be done at the time of the initial evaluation (undiagnosed / untreated patients), then at one year of follow-up. |
|
Score of borderline personality symptoms (BSL scale)
| At inclusion |
| Characterization of emotional dysregulation (descriptive analysis of different scales assessing emotional dysregulation) | Score of borderline personality symptoms (BSL scale) | At 12 months after inclusion |
| Association between emotional dysregulation, cognitive deficits and circadian instability |
Correlation between emotional dysregulation and executive and attentional dysfunction measured with the TAP test. Correlation between emotional dysregulation and instability index of circadian rhythms measured by actimetry. |
| At 12 months after inclusion |
| Strasbourg |
| 67091 |
| France |