Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

ERCP Based Study of Microbiota in Bile From Patients With Common Bile Duct Stone

In this study, investigators will investigate the microbiota of bile in common bile duct stone participants. Three key questions are of concern. The first one is whether there is bacteriria in bile in participants without common bile duct stone. The second one is whether the microbiota of bile is similar with that of gut mucosa in common bile duct stone participants. The third one is whether the bacteria in bile of common bile participants with intact papillar is the same as that of participants underwent sphinctomy.

Inclusion Criteria:

• CBD tumor or CBD calculi

Exclusion Criteria:

• contraindication for ERCP