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The Transversus Abdominis Plane (TAP) block is the current standard of care for patients undergoing laparoscopic abdominal surgeries with the Enhanced Recovery After Surgery (ERAS) Protocol. The Quadratus Lumborum (QL) is another established abdominal fascial plane block that is comparable in procedure and risks and may potentially be more beneficial. The study compares the two blocks in hopes of establishing a new standard of care for patients undergoing laparoscopic abdominal surgeries with the ERAS protocol.
The Transversus Abdominis Plane (TAP) block is the current standard of care for patients undergoing laparoscopic abdominal surgeries with the Enhanced Recovery After Surgery (ERAS) Protocol. The Quadratus Lumborum (QL) is another established abdominal fascial plane block that is comparable in procedure and risks and may potentially be more beneficial. The study compares the two blocks in hopes of establishing a new standard of care for patients undergoing laparoscopic abdominal surgeries with the ERAS protocol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control - Transversus Abdominus Plane Block | Active Comparator | Standardized ERAS regional nerve block |
|
| Quadratus Lumborum Block | Experimental | Quadratus lumborum nerve block |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control - Transversus Abdominus Plane Block | Procedure | Abdominal fascial plane block - regional anesthesia |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dermatomal Mapping | The primary outcome of interest is the proportion of subjects reporting a positive block. This is determined by dermatomal mapping in cephalad direction in PACU within 6 hours of TAP or QL placement. A positive outcome is one where the QL block measures 2 or more dermatomal levels higher than the TAP block | 6 hours |
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Inclusion Criteria:
• Patients scheduled for laparoscopic abdominal surgery as posted by the surgeon
Exclusion Criteria:
• Patient inability to consent
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| Name | Affiliation | Role |
|---|---|---|
| Renuka M George, MD | Medical University of South Carolina | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Medical University of South Carolina | Charleston | South Carolina | 29425 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39510803 | Derived | George RM, McSwain JR, Gukasov M, Wilson DA, Nitchie H, Wilson SH. Dermatomal spread in lateral quadratus lumborum blocks versus transversus abdominus plane blocks after laparoscopic colorectal surgery: a randomized clinical trial. Reg Anesth Pain Med. 2026 Feb 5;51(2):181-186. doi: 10.1136/rapm-2024-105488. |
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The expected cephalad dermatomal distribution of the TAP block is T10. A positive outcome is a QL block with patient anesthesia at 2 or more dermatomes higher than the TAP block. The investigators will assume that there is a 30% difference between the two blocks, which leads to between 24 and 33 patients in each arm (ideally aiming for 30 patients in each group).
The investigators have included other sample sizes should they find that there is a higher or lower percentage difference between the QL and TAP blocks.
Outcome: A positive block is considered anesthesia at T8 or above and a negative block is considered analgesia below T8
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Outcome assessor and patient blinded to type of block that the patient receives. Outcome assessor will check dermatomal levels after surgery.
| Quadratus Lumborum Block | Procedure | Abdominal fascial plane block - regional anesthesia |
|