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| Name | Class |
|---|---|
| Clinical Hospital Centre Zagreb | OTHER |
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All kidney transplant recipients require immunosuppression, the net level of which is difficult to assess. Current practice in assessing immune reactivity is to monitor levels of some immunosuppressive drugs. QuantiFERON Monitor® (QFM) is an in vitro diagnostic test that detects interferon-γ (IFN-γ) release in peripheral blood. Its clinical utility in assessment of the net state of immunosuppression in kidney transplant recipients has not been well studied. The aim of our study is to evaluate the discriminating value of QFM testing results for infection and rejection in a single-centre cohort of kidney transplant recipients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Kidney transplant recipients without clinical/laboratory/biopsy signs of infection or graft rejection | ||
| Infection | Kidney transplant recipients presenting with clinical or laboratory signs of infection (bacterial or viral) | ||
| Rejection | Kidney transplant recipients presenting with clinical, laboratory or biopsy signs of graft rejection. |
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| Measure | Description | Time Frame |
|---|---|---|
| Infection | Interferon gamma level in patients with infection | throughout the study period (Kidney transplant recipients from 1 day date of tx to 15 years after tx) |
| Measure | Description | Time Frame |
|---|---|---|
| Rejection | Interferon gamma levels in patients with rejection | throughout the study period (Kidney transplant recipients from 1 day date of tx to 15 years after tx) |
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Inclusion Criteria:
Exclusion Criteria:
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Kidney transplant recipients
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ivan Margeta, MD | Contact | +385921384970 | ivan.margeta@kb-merkur.hr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Hospital Merkur | Recruiting | Zagreb | HR | 10000 | Croatia |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Dec 28, 2018 | |
| Reset | Apr 1, 2019 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Dec 28, 2018 | Apr 1, 2019 |
| ID | Term |
|---|---|
| D012059 | Rejection, Psychology |
| D007239 | Infections |
| ID | Term |
|---|---|
| D012919 | Social Behavior |
| D001519 | Behavior |
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