TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer
The purpose of this study is to compare the effects on low risk breast cancer receiving usual care that includes regional radiation therapy, with receiving no regional radiation therapy. Researchers want to see if not giving this type of radiation treatment works as well at preventing breast cancer from coming back.
Women with node positive breast cancer normally will receive endocrine therapy and some may receive chemotherapy to help prevent the cancer from coming back. Many women will also receive radiotherapy to the whole breast/chest area and the surrounding lymph glands (called regional radiotherapy). No one really knows whether patients with low risk breast cancer need to receive regional radiotherapy. Some women may be getting regional radiotherapy who do not need it. These women may be exposed to the side effects of their treatment without benefit.
Inclusion Criteria:
Exclusion Criteria:
Deerfield Beach, Florida 33442, United States
Miami, Florida 33136, United States
Highland Park, Illinois 60035, United States
Louisville, Kentucky 40202, United States
Baltimore, Maryland 21237, United States
Grand Rapids, Michigan 49503, United States
Lebanon, New Hampshire 03756, United States
New York, New York 10032, United States
Harrisburg, Pennsylvania 17109, United States
Mechanicsburg, Pennsylvania 17050, United States
Hilton Head Island, South Carolina 29926, United States
Houston, Texas 77030, United States
American Fork, Utah 84003, United States
Berlin Corners, Vermont 05602, United States
Johnson Creek, Wisconsin 53038, United States
Madison, Wisconsin 53718, United States
Madison, Wisconsin 53792, United States
Stevens Point, Wisconsin 54482, United States
Sturgeon Bay, Wisconsin 54235-1495, United States
Summit, Wisconsin 53066, United States
Saint John, New Brunswick E2L 4L2, Canada
Saint Catharines, Ontario L2S 0A9, Canada
Montreal, Quebec H3H 2R9, Canada