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Transthoracic lung biopsy (TLB) provides a histological diagnosis of nodule or lung mass. Pneumothorax is the main complication of TLB with an average of 20%. Many risk factors, whether clinical, computed tomography or related to TLB, are described in the literature. The British Thoracic Society recommends monitoring for 2 hours after the procedure with a possible discharge if the chest X-ray is normal. There is no French or European recommendation for monitoring the occurrence of pneumothorax after TLB. In the university center of Besançon, France, a minimum supervision of 4 hours is recommended and approximately one in two patients is hospitalized until the following day to reach this minimum time of 4 hours. The objective of the SPOT study is to perform a predictive score of pneumothorax from a retrospective cohort of patients for whom a transthoracic lung biopsy was performed and to validate this score on a prospective cohort. The expected goal is to select patients who can benefit from outpatient care by shortening the post-procedure surveillance period and to monitor more long-term only high-risk patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retrospective cohort | All patients having a CT-guided transthoracic biopsy from September 2012 and September 2017. |
| |
| Prospective cohort | All patients having a CT-guided transthoracic biopsy from April 2018. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Needle lung biopsy | Procedure | Needle lung biopsy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pneumothorax occurrence | Pneumothorax is defined by the observation on the chest x-ray of a pleural detachment regardless of its importance. | between 4 and 24 hours after procedure |
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Inclusion Criteria:
Exclusion Criteria:
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See eligibilty criteria
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Joffrey Hamam | Contact | 0381668802 | +33 | joffrey.hamam@live.fr |
| Jean-Charles Dalphin | Contact | 0381668802 | +33 | jean-charles.dalphin@univ-fcomte.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Besançon | Recruiting | Besançon | Doubs | 25000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37603106 | Derived | Lamfichekh Y, Lafay V, Hamam J, Guillien A, Puyraveau M, Behr J, Manzoni P, Calame P, Dalphin JC, Eberst G, Grillet F, Westeel V. Score to Predict the Occurrence of Pneumothorax After Computed Tomography-guided Percutaneous Transthoracic Lung Biopsy. J Thorac Imaging. 2023 Sep 1;38(5):315-324. doi: 10.1097/RTI.0000000000000729. Epub 2023 Jul 17. |
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| ID | Term |
|---|---|
| D011030 | Pneumothorax |
| ID | Term |
|---|---|
| D010995 | Pleural Diseases |
| D012140 | Respiratory Tract Diseases |
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