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Aim: To assess whether there are different training effects on glucose concentration and cardiorespiratory parameters of different high-intensity training protocols in patients with type 2 diabetes.
Type 2 diabetes is a highly prevalent disease associated with cardiovascular disease leading to high levels of mortality, morbidity and health expenditure, characterized by impaired glucose control during activities and reduced aerobic exercise capacity .
Exercise training is the most effective way to improve compliance, reduce blood glucose concentration and increase insulin sensitivity. Training increases muscle capacity, oxidative capacity and glucose transport, peripheral insulin sensitivity is improved.
Exercise training with high-intensity interval (resting and exercise period) High Intensity Interval Training (HIIT) is a form of exercise training that has recently been widely used in the management of type 2 diabetes, including short duration high intensity exercise periods and lower severity or passive rest periods. There are different HIIT exercise training programs according to physiological responses in the literature. However, long-term and short-term HIIT training training programs were not compared in terms of their effect on glucose concentration and cardiorespiratory fitness. The aim of this study was to compare the effects of different HIIT exercise training programs so that exercise programs for patients with type 2 diabetes could be planned more effectively.
This study will be participated patients with Type 2 diabetes. Patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life will be evaluated.
Pulmonary function test will be assesed with spirometer, respiratory muscle strength will be evaluated with mouth pressure. Exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test, cycle ergometer. Muscle oxigeneration will be asssed with wearable lactate threshold predicting device. Physical activity level will be evaluated trial accelerometer.
Then, patients will be randomly divided two high intensity interval exercise training groups.
First group: short duration high intensity exercise training (Exercise load phase : 30sn %100 Patients performance, rest phase: 120sn %25 patients performance) Second group: Long duration high intensity interval exercise training (Exercise load phase : 4 dk %100 Patients performance, rest phase: 120sn %25 patients performance) All patients will participate three times a week during eight weeks. The muscle oxigeneration, blood glucose consantration, blood pressure, heart rate will be recorded before and after each exercise session. After 8 week, all test will be done again.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| short duration group | Experimental | 30sn %100 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks |
|
| long duration group | Experimental | 4dk %85 Wmax 120sn %25 Wmax 3 sessions/week total 8 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Short duration | Other | exercise Short duration high intensity training |
|
| Measure | Description | Time Frame |
|---|---|---|
| muscle oxigeneration | It is evaluate with wearable lactate threshold device on gastrocinemius | Change from baseline muscle oxigeneration at 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The blood glucose consentration | It is evaluate with sample from blood | before and after 8 weeks |
| Functional Exercise capacity | İt is evaluated with six minute walk test |
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Inclusion Criteria:
Exclusion Criteria:
Individuals have known lung disease,have undergone any cardiac event or surgery within the past six months, have uncontrolled hypertension, and have diabetic complications such as nephropathy, retinopathy and severe neuropathy.
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| Name | Affiliation | Role |
|---|---|---|
| Cemile Bozdemir Özel, McS | Hacettepe University Physiotherapy and Rehabilitation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hacettepe University | Ankara | State | 06100 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| Long duration | Other | exercise Long duration high intensity training |
|
|
| before and after 8 weeks |
| Maximal exercise capacity | İt is evaluated using with incremental shuttle test | before and after 8 weeks |
| Symptom limited maximal exercise capacity | İt is evaluated with cycle ergometer test | before and after 8 weeks |
| Lipit profile-High density lipoprotein cholesterol | High density lipoprotein cholesterol wiil be assesed | before and after 8 weeks |
| Lipit profile- low density lipoprotein cholesterol | low density lipoprotein cholesterol wiil be assesed | before and after 8 weeks |
| Lipit profile- trigliseride | trigliseride wiil be assesed | before and after 8 weeks |
| pulmonary parameter-Forced vital capacity | Forced vital capacity will be evaluated | before and after 8 weeks |
| pulmonary parameter-Forced vital capacity in the first second | Forced vital capacity in the first second will be evaluated | before and after 8 weeks |
| pulmonary parameter-Mid expiratory flow rate | Mid expiratory flow rate will be evaluated | before and after 8 weeks |
| pulmonary parameter-Peak expiratory flow | Peak expiratory flow will be evaluated | before and after 8 weeks |
| Respiratory muscle strength | It is evaluated with mouth pressure | before and after 8 weeks |
| Physical activity level | ıt is assessed using accelerometer | before and after 8 weeks |