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Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods of anesthesia are currently being used to achieve this goal.
The aim of the study was to assess the effectiveness of Long thoracic nerve bloc on postoperative VATS analgesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Grup L | Experimental | IV patient-controlled analgesia (PCA) morphine + Ultrasound guided Long thoracic nerve blockage with 5 ml % 0.25 bupivacaine |
|
| Group P | Active Comparator | IV patient-controlled analgesia (PCA) morphine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Morphine Sulfate | Drug | Intravenous morphine infusion with PCA: Solution was concentration of 0.5 mg/mL. Loading dose of 1 mg, 0.5 mg of bolus dose and 20 min of locking time. |
|
| Measure | Description | Time Frame |
|---|---|---|
| morphine consumption | morphine consumption | Postoperative 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale | Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0=no pain, 10=intolerable pain) | Postoperative 24 hours |
| side effect (Hypotension) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| korgün Ökmen, M.D | Contact | +902242955000 | korgunokmen@gmail.com | |
| Burcu Metin Ökmen, M.D | Contact | +902242955000 | burcumetinokmen@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Korgün Ökmen, M.D | Bursa Yuksek Ihtisas Training and Research Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D009020 | Morphine |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D009022 | Morphine Derivatives |
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
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Prospective, randomized, controlled, single-blind
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|
| Bupivacaine | Drug | Ultrasound guided Long thoracic nerve blockage with 5 ml % 0.25 bupivacaine |
|
side effect Hypotension
| Postoperative 24 hours |
| additional analgesic use | additional analgesic use | Postoperative 24 hours |
| side effect (Nausea and vomiting) | Nausea and vomiting scale 1. Nausea and vomiting scale (nausea-vomiting scale (NVS): 1. No nausea is present, 2. Mild nausea is present. 3. Severe nausea is present. 4. Vomiting is present) In case of a NVS score of >3, an anti-emetic drug was administered. | Postoperative 24 hours |
| side effect (Ramsay Sedation Scale (RSS) | Ramsay Sedation Scale (Ramsay Sedation Scale (RSS) : 1. Anxiety, agitation are present; 2. Cooperated, awake; 3. Sedatized, response to commands; 4. Sleepy, immediately awoken by auditory stimulus or glabella tap; 5. Sleepy, deep response to auditory stimulus or glabella tap and 6. Sleepy, no response to auditory stimulus or glabella tap) | Postoperative 24 hours |
| D006571 |
| Heterocyclic Compounds |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |