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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01MD012778-01A1 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Minority Health and Health Disparities (NIMHD) | NIH |
| Thomas Jefferson University | OTHER |
| University of Maryland, College Park | OTHER |
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The objective of the study is to conduct a randomized controlled trial to determine the impact of a multi-level culturally-sensitive decision support intervention on colorectal cancer screening adherence among 400 Chinese and Korean American primary care patients.
This study culturally adapts existing evidence-based decision support navigation intervention and tests its efficacy among 200 Chinese and Korean American men and 200 Chinese and Korean American women aged 50 to 75 eligible for colorectal cancer screening. Participants are recruited from primary care physician clinics. The study is designed to compare colorectal cancer screening outcomes between the decision support navigation intervention and the advanced control. Those randomized to the advanced control group only receives an informational booklet, a stool blood test kit and a reminder by mail. Those randomized to the decision support navigation intervention group receives everything the advanced control group receives as well as decision support and navigation contacts. Investigators in the study develop an individualized screening plan using a theory-based online Decision Counseling Program, share the plan with the participants' primary care physicians, and have primary care physicians to encourage the colorectal cancer screening to participants. Using outcomes data collected by survey and medical record review, this study: (1) determines overall colorectal cancer screening adherence in the culturally adapted decision support navigation intervention vs. the advanced control; (2) measures change in colorectal cancer screening decision stage in the culturally adapted decision support navigation intervention vs. the advanced control; and (3) assesses colorectal cancer screening test-specific (stool blood test vs. colonoscopy) adherence in the culturally adapted decision support navigation intervention vs. the advanced control. Additionally, investigators in the study evaluate intervention reach, effectiveness, adoption, implementation, and maintenance using interview data.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Advanced Control | Active Comparator | The advanced control group receives a set of standard materials regarding colorectal cancer screening. |
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| Culturally Adapted Decision Support Navigation Intervention | Experimental | The culturally adapted decision support navigation intervention group receives everything advanced group receives as well as decision support and navigation contacts. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Advanced Control | Behavioral | Participants receive linguistically and culturally tailored information booklet on colorectal cancer and colorectal cancer screening, colonoscopy instructions, stool blood test kits and reminder by mail. Participants' height, weight, and waist/hip circumference, blood pressure, blood glucose, and cholesterol levels will be measured by trained research staff. Participants will also receive the result of body measurements right away as a free service. |
| Measure | Description | Time Frame |
|---|---|---|
| Colorectal cancer screening adherence at 6 months by medical record review | Measure overall colorectal cancer screening adherence at 6 months by medical record review. | 6 months |
| Colorectal cancer screening adherence at 6 months by self-report | Measure overall colorectal cancer screening adherence at 6 months by self-report during 6-month survey (by phone). | 6 months |
| Overall colorectal cancer screening adherence at 12 months by medical record review | Measure overall colorectal cancer screening adherence at 12 months by medical record review. | 12 months |
| Overall colorectal cancer screening adherence at 12 months by self-report | Measure overall colorectal cancer screening adherence at 12 months by self-report (by phone interview). | 12 months |
| Colorectal cancer screening decision stage at baseline (Stool Blood Test) | Measure colorectal cancer screening decision stage for stool blood test at baseline. | Baseline |
| Colorectal cancer screening decision stage at 6-months (Stool Blood Test) | Measure colorectal cancer screening decision stage for stool blood test at 6 months. | 6 months |
| Change in colorectal cancer screening decision stage between baseline and 6 months (Stool Blood Test) | Measure change in colorectal cancer screening decision stage for stool blood test between baseline and 6 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Knowledge about colorectal cancer and colorectal cancer screening (Baseline) | Measure knowledge about colorectal cancer and colorectal cancer screening at baseline. | Baseline |
| Knowledge about colorectal cancer and colorectal cancer screening (6 months) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sunmin Lee, ScD | UC Irvine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California, Irvine | Irvine | California | 92697 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38303653 | Derived | Morey BN, Shi Y, Ryu S, Redline S, Kawachi I, Park HW, Lee S. Risk of sleep apnea associated with higher blood pressure among Chinese and Korean Americans. Ethn Health. 2024 Apr;29(3):295-308. doi: 10.1080/13557858.2024.2311417. Epub 2024 Feb 2. | |
| 36701271 | Derived | Morey BN, Ryu S, Shi Y, Lee S. The Mediating Role of Sleep Disturbance on the Association Between Stress and Self-Rated Health Among Chinese and Korean Immigrant Americans. Prev Chronic Dis. 2023 Jan 26;20:E04. doi: 10.5888/pcd20.220241. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Sep 25, 2018 | Jun 9, 2021 |
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| Culturally-Adapted Decision Support Navigation Intervention | Behavioral | Participants in this group receive everything that advanced control group receives. In addition to a set of standard materials, they receive culturally and linguistically adapted decision counseling from the patient navigator. The patient navigator develops an individualized colorectal cancer screening plan using a theory-based online Decision Counseling Program. After the Program is completed, the patient navigator develops individualized colorectal cancer screening plan and shares the information with participants and participants' primary care physicians. Then, primary care physicians encourage the colorectal cancer screening to participants. |
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| Baseline and 6 months |
| Colorectal cancer screening decision stage at baseline (Colonoscopy) | Measure colorectal cancer screening decision stage for colonoscopy at baseline. | Baseline |
| Colorectal cancer screening decision stage at 6 months (Colonoscopy) | Measure colorectal cancer screening decision stage for colonoscopy at 6 months. | 6 months |
| Change in colorectal cancer screening decision stage between baseline and 6 months (Colonoscopy) | Measure change in colorectal cancer screening decision stage for colonoscopy between baseline and 6 months. | Baseline and 6 months |
| Colorectal cancer screening test-specific adherence at 6 months (Stool Blood Test) | Measure the fraction of participants who undergo a stool blood test at 6 months. | 6 months |
| Colorectal cancer screening test-specific adherence at 6 months (Colonoscopy) | Measure the fraction of participants who undergo a colonoscopy at 6 months. | 6 months |
| Colorectal cancer screening test-specific adherence at 12 months (Stool Blood Test) | Measure the fraction of participants who undergo a stool blood test at 12 months. | 12 months |
| Colorectal cancer screening test-specific adherence at 12 months (Colonoscopy) | Measure the fraction of participants who undergo a colonoscopy at 12 months. | 12 months |
Measure knowledge about colorectal cancer and colorectal cancer screening at 6 months. |
| 6 months |
| Change in knowledge about colorectal cancer and colorectal cancer screening between baseline and 6 months | Measure change in knowledge score about colorectal cancer and colorectal cancer screening between baseline and 6 months. | Baseline and 6 months |
| 36622567 | Derived | Lee S, Ryu S, Lee GE, Redline S, Morey BN. Risk of Sleep Apnea Is Associated with Abdominal Obesity Among Asian Americans: Comparing Waist-to-Hip Ratio and Body Mass Index. J Racial Ethn Health Disparities. 2024 Feb;11(1):157-167. doi: 10.1007/s40615-022-01507-z. Epub 2023 Jan 9. |
| 35705844 | Derived | Morey BN, Ryu S, Shi Y, Park HW, Lee S. Acculturation and Cardiometabolic Abnormalities Among Chinese and Korean Americans. J Racial Ethn Health Disparities. 2023 Aug;10(4):1605-1615. doi: 10.1007/s40615-022-01347-x. Epub 2022 Jun 15. |
| 34922392 | Derived | Lee S, Ryu S, Lee GE, Kawachi I, Morey BN, Slopen N. The association of acculturative stress with self-reported sleep disturbance and sleep duration among Asian Americans. Sleep. 2022 Apr 11;45(4):zsab298. doi: 10.1093/sleep/zsab298. |
| Prot_003.pdf |
| SAP | No | Yes | No | Statistical Analysis Plan | Mar 1, 2018 | Jun 9, 2021 | SAP_004.pdf |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
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