Voluntary Drug Poisoning by Psychoactive Molecules: Identify Cognitive Markers

Voluntary Drug Poisoning by Psychoactive Molecules: Identify Cognitive Markers Predictive of a Preserved Memory of Care in Psychiatric Emergencies

To identify in patients admitted for Voluntary drug poisoning (IMV) by psychoactive substances, T1 predictors of T2 recall of psychiatric interview and care project.

The methodology will compare the episodic memory results of patients admitted for IMV who have exclusively ingested amnesic substances to a subject control group that has made IMV with non-amnesic substances such as paracetamol. The purpose of this comparison is to ensure that memory problems are not related to the context of the suicidal crisis.

The second step will be able to relate the memory score of the predictor variables. To achieve this, it will perform a multivariate linear regression in each group in order to confirm the results of the pilot study and to be able to regress in the control group which was not possible in the pilot study because of the lack of effective.

Finally, this study will try to establish, using Receiver Operating Characteristic (ROC) curves, thresholds for cognitive scores and begin to develop a tool for clinical practice.

Inclusion Criteria:

Group amnesic substances :

• Age from 18 to 65 years
• Admitted to emergencies for IMV by benzodiazepines
• Supported at Toulouse University Hospital (hospitalization, outpatient)

Group control :

• Age from 18 to 65 years
• Admitted to emergencies for IMV by non-depressive substances of the central nervous system
• Supported at Toulouse University Hospital (hospitalization, outpatient)

Exclusion Criteria:

• Cognitive Disorder Due to an Organic Disorder Neuro Degenerative Disease, Korsakoff Syndrome) or Mental Retardation Diagnosed
• Patient under guardianship
• Not speaking and / or not reading French
• Neurodegenerative disease diagnosed