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| Name | Class |
|---|---|
| Hanmi Pharmaceutical Company Limited | INDUSTRY |
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To investigate the rate and risk factors of stroke or systemic embolism (SE) following atrial fibrillation (AF) ablation.
Since catheter ablation for AF reduces the burden of AF effectively, several studies have demonstrated that catheter ablation not only improves the quality of life but also reduces the risk of stroke and all cause mortality. However, until now the guideline has recommended the continuation of oral anticoagulation (OAC) therapy in patients who are at risk of stroke or systemic embolism (SE) based on the CHA2DS2-VASc score, even though they have sinus rhythm following catheter ablation. The aims of this retrospective study is to assess the rate of stroke/SE during follow-up period after AF ablation and identify the independent risk factors for stroke/SE in patients who underwent catheter ablation for AF.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stroke group | Patients who experienced stroke or systemic embolic event following catheter ablation for AF. | ||
| Control group | Patients who did not experienced stroke or systemic embolic event following catheter ablation for AF. |
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of stroke or systemic embolism after AF ablation | Risk factors for stroke or systemic embolism after AF ablation | From the time of catheter ablation until the date of the last visit or the date of event.(Retrospective period of up to 20 years) |
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Inclusion Criteria:
Exclusion Criteria:
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Study population was extracted from a consortium of registry of AF ablation by three University Hospitals (Korea univ Guro, Korea univ Anam and Seoul National University) from 1998 to 2016.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Korea University Anam Hospital | Seoul | South Korea | ||||
| Korea University Guro Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31502330 | Derived | Ahn J, Shin SY, Shim J, Kim YH, Han SJ, Choi EK, Oh S, Shin JY, Choe JC, Park JS, Lee HW, Oh JH, Choi JH, Lee HC, Cha KS, Hong TJ, Lip GYH, Lim HE. Association between epicardial adipose tissue and embolic stroke after catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2019 Nov;30(11):2209-2216. doi: 10.1111/jce.14154. Epub 2019 Sep 19. |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| Seoul |
| South Korea |
| Seoul National University Hospital | Seoul | South Korea |
| D013568 |
| Pathological Conditions, Signs and Symptoms |