The objective of the study is to determine which of the two commonly used endodontic medications (Eugenol VS Articaine) is most effective in controlling postoperative pain in irreversible pulpitis of the mature permanent tooth in adults. To do so, an assessment of the pain felt by patients will be carried out a few days apart. The supposed results are that the medications are equivalent in terms of effectiveness on the pain, but could then present different economic arguments

In irreversible pulpitis of the mature permanent tooth, the enrolled patients receive endodontic medications (Eugenol or Articaine) in order to determine which one is the more efficient to control the pain.

These patients would have received the same medication without this study. That's why this is an obsevationnal study.

Inclusion Criteria:

• Adult patient, major, affiliated to a social health insurance scheme
• Patient having agreed to participate in the study
• Urgent consultant patient for irreversible pulpitis
• Patient understanding French

Exclusion Criteria:

• Refusal of the patient to participate in the study
• Impossibility of performing the surgical procedure
• Impossibility to give the subject information enlightened (difficulty of understanding ...)
• Subject under the protection of justice, or under guardianship
• General contraindication to endodontic treatment in 2 sessions (high risk of infectious endocarditis, for example)
• Chronic intake of analgesic drugs

Patients from the University Hospital (Dental Service) of Strasbourg (HUS)