Cooperative Pain Education and Self-management: Expanding... | NCT03469505

ID	Type	Description	Link
1UG3AT009767-01	U.S. NIH Grant/Contract		View source
4UH3AT009767-03	U.S. NIH Grant/Contract		View source

Name	Class
National Center for Complementary and Integrative Health (NCCIH)	NIH

Label	Type	Description	Intervention Names
data from veterans using COPES	Active Comparator	Data from veterans using COPES for chronic pain	Behavioral: COPES
data from veterans using CBT-CP	Active Comparator	Data from veterans using CBT-CP for chronic pain	Behavioral: CBT-CP

Name	Type	Description	Arm Group Labels	Other Names
COPES	Behavioral	Cooperative Pain Education and Self-Management for chronic pain therapy.	data from veterans using COPES

Measure	Description	Time Frame
Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score	The BPI-I Score is patient-reported pain-related interference. BPI-I score range is 0 to 10. Higher scores indicate worse functioning.	4 months

Measure	Description	Time Frame
Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score	The BPI-I Score is patient-reported pain-related interference. BPI-I score range is 0 to 10. Higher scores indicate worse functioning.	6 months
Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score

Name	Affiliation	Role
Alicia Heapy, Phd	VA Office of Research and Development	Principal Investigator

Facility	Status	City	State	ZIP	Country	Contacts
Edward Hines, Jr. VA Hospital		Hines	Illinois	60141	United States
VA Central Western Massachusetts

PubMed Identifier	Type	Citation	Retractions
42340733	Derived	Heapy AA, Driscoll MA, Edmond S, LaChappelle KM, Buta E, Halat A, Krein SL, Martino S, DeBar L, Murphy JL, Mattocks K, Coleman BC, Ruser C, Piette JD, MacLean RR, Ankawi B, Cervone D, Wagner TH, Higgins DM. Self-Directed vs Clinician-Delivered Cognitive Behavioral Therapy for Chronic Pain: A Randomized Clinical Trial. JAMA. 2026 Jun 24:1-13. doi: 10.1001/jama.2026.7861. Online ahead of print.

ID	Title	Description
FG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
FG001	Data From Veterans Using CBT-CP

Type	Includes Protocol	Includes SAP	Includes ICF	Document Label	Document Date	Document Uploaded Date	Document File Name
Prot_SAP	Yes	Yes	No	Study Protocol and Statistical Analysis Plan	Apr 17, 2025

ID	Title	Description
BG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain
BG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain
BG002	Total	Total of all reporting groups

Units	Counts
Participants	BG000384 BG001380 BG002764

Baseline Measures

Title

Description

Population Description

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Denominator Units Selected

Denominators

Classes

Age, Continuous

Mean

Standard Deviation

years

Title

Denominators

Categories

Title	Measurements
	BG00053.0± 12.3 BG00152.7± 12.2 BG00252.8± 12.3

Sex: Female, Male

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Female	BG000149 BG001150 BG002

Race (NIH/OMB)

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
American Indian or Alaska Native	BG0004 BG0013 BG002

Ethnicity (NIH/OMB)

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Hispanic or Latino	BG00062 BG00145 BG002

Brief Pain Inventory-Interference (BPI-I) subscale

BPI-I score range is 0 to 10. Higher scores indicate worse functioning.

Mean

Standard Deviation

pain interference score

Title

Denominators

Categories

Title	Measurements
	BG0006.7± 1.8 BG0016.8± 1.8

Pain, Enjoyment, General activity scale(PEG)- 3 item

PEG-3 score range is 0-10. Higher scores indicate more pain impact (intensity and interference).

Mean

Standard Deviation

PEG-3 score

Title

Denominators

Categories

Title	Measurements
	BG0006.8± 1.5 BG0016.9

Patient Health Questionnaire-(PHQ) 8 item

PHQ-8 score range is 0-24; ≥10 indicates clinically significant depressive symptoms. Higher scores indicate more depressive symptomatology.

Mean

Standard Deviation

Depression symptom score

Title

Denominators

Categories

Title	Measurements
	BG00015.9± 5.8 BG001

Pain Catastrophizing Scale, Short Form (PCS-SF)

PCS-SF with 3 items; global score range is 3-15. Higher scores indicate more catastrophizing thinking.

Mean

Standard Deviation

Catastrophizing thinking score

Title

Denominators

Categories

Title	Measurements
	BG00010.9± 3.0 BG001

Insomnia Severity Index (ISI)

ISI score range 0-28, higher scores indicate higher sleep difficulty, (15 or above indicates clinical insomnia)

Mean

Standard Deviation

sleep hygiene symptom score

Title

Denominators

Categories

Title	Measurements
	BG00020.5± 5.6 BG00120.6

Pain Self-Efficacy Questionnaire, Short Form (PSEQ-SF)

PSEQ-SF score range 0- 10. Higher scores indicate higher pain self-efficacy.

Mean

Standard Deviation

pain self-efficacy score

Title

Denominators

Categories

Title	Measurements
	BG0004.2± 2.5 BG0014.2± 2.7

Numeric Rating Scale (NRS), Pain Intensity

Pain NRS score on average in the last week, scores range from 0 (no pain) to 10 (worst pain imaginable).

Mean

Standard Deviation

pain score

Title

Denominators

Categories

Title	Measurements
	BG0006.7± 1.4 BG0016.7

Study Site

Participants enrolled in this trial were located at nine Medical Centers across the US.

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Site 1	BG00020 BG00118 BG002

Type

Title

Description

Population Description

Reporting Status

Anticipated Posting Date

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Time Frame

Units Analyzed

Denominator Units Selected

Arm/Group Information

Denominators

Classes

Analyses

Primary

Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score

The BPI-I Score is patient-reported pain-related interference. BPI-I score range is 0 to 10. Higher scores indicate worse functioning.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000384 OG001380

Title

Denominators

Categories

Title	Measurements
	OG0005.26± 0.15 OG0016.23± 0.13

Group IDs	Group Description	Statistical Method	Statistical Comment	P-Value	P-Value Comment	Parameter Type	Parameter Value	Dispersion Type	Dispersion Value	Confidence Interval Sides	Confidence Interval %	CI Lower Limit	CI Upper Limit	CI Lower Limit Comment	CI Upper Limit Comment	Estimate Comment	Tested Non-Inferiority	Non-Inferiority Type	Non-Inferiority Comment	Other Analysis Description
OG000 OG001		Mixed Models Analysis	This mixed model for repeated measures includes baseline values of the outcome with the constraint that the 2 group means were equal at baseline.	<0.0001		Mean Difference (Final Values)	-0.98			2-Sided	95	-1.31	-0.65			Negative values indicate better functioning from baseline to the timepoint in the COPES group. Positive values indicate better functioning from baseline to the timepoint in the CBT-CP group.		Superiority

Secondary

Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score

The BPI-I Score is patient-reported pain-related interference. BPI-I score range is 0 to 10. Higher scores indicate worse functioning.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

6 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Brief Pain Inventory, Interference Subscale (BPI-I) Score

The BPI-I Score is patient-reported pain-related interference. BPI-I score range is 0 to 10. Higher scores indicate worse functioning.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

12 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Pain, Enjoyment, General Activity Scale (PEG-3) Score

The PEG-3 is a three-Item Scale Assessing Pain Intensity and Interference. Data was collected through automated IVR calls with a range from 0-10. Higher scores indicate more pain impact (intensity and interference).

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 month

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Patient Health Questionnaire (PHQ-8) Score

PHQ-8 is a Depression symptom severity scale will be assessed using the 8-item a widely-used measure with excellent internal consistency and stability.PHQ-8 score range is 0-24; ≥10 indicates clinically significant depressive symptoms. Higher scores indicate more depressive symptomatology.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Pain Catastrophizing Scale (PCS)- Short Form

The Pain Catastrophizing Scale (PCS)-Short Form is a validated, 3-item self-report scale that examines thoughts and feelings people may experience when they are in pain. Total score range 3-15 with higher scores indicating more catatrophizing.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Insomnia Severity Index (ISI) Score

Sleep quality was measured using the ISI and will assess subjective sleep quality. ISI score range 0-28, higher scores indicate higher sleep difficulty, (15 or above clinical insomnia).

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Mean Pain Self-Efficacy Questionnaire (PSEQ) Score

Self-Efficacy will be assessed using 1-Item of the PSEQ.PSEQ score range 0- 10. Higher scores indicate higher pain self-efficacy.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Patient Global Perception of Change (PGIC)

The Patient Global Perception of Change scale is a single item measure that quantifies a participant's overall perception of improvement since beginning treatment and the clinical importance of that improvement. Participants indicate improvement on a 1-7s scale with 1 as "much worse" to "much better" scale. For PGIC (ordinal) data repored is number of participants with at least moderate improvement (score>=5).

Posted

Count of Participants

Participants

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain

Units	Counts
Participants	OG000

Secondary

Mean Pain Satisfaction Questionnaire Score

Pain satisfaction will be measured using an adapted Pain Satisfaction Questionnaire. This 5-item measure about patient self report of experience of treatment . The questions are on a scale from (0=very dissatisfied to 4=very satisfied). Total score range 0-4 with higher scores indicating more satisfaction.

Data presented here is from those who completed the 4 month assessment.

Posted

Least Squares Mean

Standard Error

score on a scale

4 month

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Secondary

Difference in Treatment Dose

Number of cognitive behavioral therapy for chronic pain sessions or COPES sessions attended for this treatment. Data presented is the number of sessions completed by expected number of sessions, among participants who initiated treatment.

Those participants who initiated treatment in each condition.

Posted

Median

Inter-Quartile Range

percentage of expected sessions

Up to 12 months post baseline

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain

Units	Counts
Participants	OG000

Secondary

Mean Numeric Rating Score (NRS), Pain Intensity Score

Average pain intensity NRS rating (over past week) range is 0-10. Higher scores indicate more pain.

This is an intent to treat analysis with all randomized participants being analyzed.

Posted

Least Squares Mean

Standard Error

score on a scale

4 months

ID	Title	Description
OG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain COPES: Cooperative Pain Education and Self-Management for chronic pain therapy.
OG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain CBT-CP: Cognitive Behavioral Therapy for Chronic Pain

Units	Counts
Participants	OG000

Serious Adverse Events

Term	Organ System	Assessment Type	Statistical Information
Abdominal Pain	Gastrointestinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0012 affected380 at risk
Abdominal Pain and Fever	Gastrointestinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Abdominal Pain, Acute Appendicitis, Surgery and Follow Up	Gastrointestinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Abdominal pain, Diarrhea, Vomit	Gastrointestinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Admission for Sleep Stabilization	Psychiatric disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Afib following cardiac ablation	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Ankle Arthroplasty	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Appendectomy	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Appendicitis and Surgery	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Arm, Knee, and back pain	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Atrial Fibrillation	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Back Pain Flare hospital stay	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Broken Right Ankle and Ongoing Dizziness; Surgery	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Buttocks Abscess and Diarrhea	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest and Back Pain	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest Pain	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Chest Pain and Cardiac Concerns	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Chest Pain and Gall Bladder Surgery	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Chest pain and headache	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Chest Pain and high blood pressure	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest Pain and Panic Attack/Distress	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest Pain and Shortness of Breath	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest Pain, shortness of breath and other symptoms	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Chest Pain/Heart Issues	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Cholecystectomy/ Pancreatitis	Endocrine disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Cholecystitis with gangrene	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Coronary Artery Disease	Vascular disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
COVID and Hospitalization	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
COVID Hospitalization	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
COVID Positive with COVID Pneumonia	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
COVID-related Hospitalization	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0011 affected380 at risk
Epilepsy-Seizure/neurological symptoms	Nervous system disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Extended Hospital Stay, Foot wound, ICU Stay through Aug-sept	General disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Fall down stairs, broken wrist and surgery	Injury, poisoning and procedural complications	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Fractured Femurs and Pelvis	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Gastrectomy	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
General hospitalization	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
GERD Surgery	Gastrointestinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Hand infection	Infections and infestations	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Head Injury and transferred to ICU; Stroke Diagnosis	Injury, poisoning and procedural complications	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Heart Palpitations	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hemoptysis	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hernia Repair	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hernia Repair surgery	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
HIDRADENITIS SUPPURATIVA	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
High Blood Pressure and Inpatient Admission	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hip Arthroplasty and Small Bowel Obstruction complications	Gastrointestinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hospital Admission for Blood in Vomit and Stool	Gastrointestinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Hospital Admission for Chest Pain and Shortness of Breath	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Hospitalization for Eye conditions	Eye disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Hospitalization-mental &social health	Psychiatric disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Infections and toe amputation	Infections and infestations	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Inpatient Admission for Psychiatric Monitoring	Psychiatric disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Inpatient Alcohol Detox	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Inpatient at hospital through 9/26 then transferred to CLC	General disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Inpatient following hernia procedure	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Inpatient hand trembling	Nervous system disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Inpatient Hospital Stay for continued cardiac issues	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
In-patient psychiatric hospitalization due to auditory hallucinations	Psychiatric disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Knee Arthroplasty and Recovery	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Knee Replacement	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Laparoscopic surgery-hemicolectomy	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Left Eye Amaurosis Fugax	Eye disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Liver Resection	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Loss of Consciousness while driving	Nervous system disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Low blood Pressure	Cardiac disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Lower abdominal wall panniculectomy	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Lower Extremity Pain and Cardiac/Neurological concerns	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Lumbar interbody fusion-posterior	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Nausea & Chest pain	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Neuro Work Up after previous inpatient stay	Nervous system disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Neurological Investigation for Fall and Weakness	Nervous system disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Pain all over	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Pancreatitis and Pneumonia	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Pancreatitis	Infections and infestations	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Pancreatitus and Cholecystectomy	Endocrine disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Pericarditis	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Persistent Heartburn	Gastrointestinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Pneumonia	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Psychiatric Admission for SI	Psychiatric disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Renal Biopsy and Bleeding	Renal and urinary disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Renal mass nephrectomy	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Right Toe Amputation and Sustained hospitalization for infection	Surgical and medical procedures	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Sepsis/Septic Shock risk and admitted to inpatient	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Septoplasty	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Shortness of Breath	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Shortness of Breath, Inpatient observation	Cardiac disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Small Bowel Obstructions and Hospitalization Stay	Gastrointestinal disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Spine Fusion	Surgical and medical procedures	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Suicidal Ideation and hospitalization	Psychiatric disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Sustained Aphasia	Nervous system disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Swelling and Admitted for monitoring of Kidney issues	Renal and urinary disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Swollen Foot and Infection	Infections and infestations	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Tachycardic and confusion symptoms	General disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Toe Wound Infection	Infections and infestations	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
UTI & Fibromyalgia sx	Renal and urinary disorders	Systematic Assessment	EG0001 affected384 at risk EG0010 affected380 at risk
Vomiting, abdominal pain, headache, nausea	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk
Weakness and Rectal Bleeding	General disorders	Systematic Assessment	EG0000 affected384 at risk EG0011 affected380 at risk

ID	Term
D010146	Pain
D009461	Neurologic Manifestations
D012816	Signs and Symptoms
D013568	Pathological Conditions, Signs and Symptoms

ID	Title	Description	Deaths (Affected)	Deaths (At Risk)	Serious Events (Affected)	Serious Events (At Risk)	Other Events (Affected)	Other Events (At Risk)
EG000	Data From Veterans Using COPES	Data from veterans using COPES for chronic pain	2	384	31	384	0	384
EG001	Data From Veterans Using CBT-CP	Data from veterans using CBT-CP for chronic pain	3	380	49	380	0	380