Several studies have described the interest of eosinopenia as a marker of infection in internal medicine or in intensive care units. Eosinopenia is an inexpensive and easily accessible biological marker of sepsis. Retrospective work in the adult emergency departments of Strasbourg University Hospitals has shown the good specificity of this biological sign for the diagnosis of infection. Our work aims to confirm the results by a more meaningful study.

Main objective: Evaluation of the interest of eosinopenia in the diagnosis of bacterial infection in ED.

Methodology: inclusion of all patients with criteria for bacterial infection in ED, inclusion of an equivalent number of uninfected control patients.

Duration : 12 months Multicentric prospective study 6 centers : Strasbourg, Hôpital Nord Franche comté, Sélestat, Wissembourg, Colmar, Mulhouse

Inclusion Criteria:

• major patient
• patient suspected of infection and benefiting from the routine practice of NFS, whatever the indication during his / her visit to the emergency room.
• patient with or without criteria for bacterial infection
• patient affiliated to a social security scheme
• patient (or legal representative) who has agreed to participate in the study

Exclusion Criteria:

• anti tumor chemotherapy
• immunosuppressive treatment
• corticotherapy
• antibiotherapy in progress
• malignant hemopathy
• evolutionary cancer
• refusal to participate in the study
• subjects under safeguard of justice
• subject under guardianship or curatorship

Any adult emergency counseling subjects who benefit from the routine practice of NFS for any indication.