Role of Dopamine Transporter in Glucose Control

Role of Dopamine Transporter in Glucose Loading of Healthy Subjects

Healthy subjects will be enrolled in this study. Each subject will be scanned twice with F18-FP-CIT PET which is commercially available. F18-FP-CIT reflects dopamine transporter availability of striatum. Before each PET scan, subject will be injected either glucose or normal saline. Therefore, PET scan will reflect the changes of dopamine transporter availability after the injection of glucose.

Inclusion Criteria:

• healthy subjects

Exclusion Criteria:

• known neurologic disorder
• known drug addiction
• known endocrine disorder