The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

Surgical-site infection is the most commonly reported nosocomial infection in patients undergoing surgery and 3rd most nosocomial infection in hospitalized patients. The SSI is associated with increases of length of hospitalization for 6 days and increases the hospital's cost by $ 300.

Because of these, prevention of SSI with appropriate antibiotic is essential.

Inclusion Criteria:

• age 18 years and above
• elective surgical patients
• No pre-surgery infection
• Do not use antibiotics before surgery
• Insensitivity to beta-lactam antibiotics

Exclusion Criteria:

• cranioplasty
• Failure to follow the patient
• The patient's unwillingness to continue participating in the research project
• Death of the patient