Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

A Randomized Trial Comparing the Effectiveness of Polyp Resection Treatments (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the resection methods.

The optimal method for removal of polyps 6-9 and 10-15 mm in size is not established. In this study, we propose to evaluate four different treatments for polyps (sized 6mm-15mm). The four treatments are cold snaring without injection, hot snaring without injection, cold EMR, and hot EMR. This study aims to help to establish the optimal resection technique for 6-9 and 10-15 mm polyps.

Inclusion Criteria:

• Aged 40 years or older
• Ability to provide informed consent

Exclusion Criteria:

• Subjects with a history of Inflammatory Bowel Disease
• Lesions less than 6mm or greater than 15mm in largest dimension