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The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who have completed a pulmonary rehabilitation.
Exercise training is an important component of the management of chronic obstructive pulmonary disease (COPD) and numerous trials have shown large improvements in health-related quality of life (HRQoL) and exercise capacity in persons with COPD. However, the great majority of patients who would benefit from pulmonary rehabilitation (PR) never follow such a program. Moreover, many COPD patients are either not instructed to exercise at all or fail to adhere to exercise training at home after completing pulmonary rehabilitation.
This study evaluates an exercise training program that requires minimal equipment (i.e., only a chair and elastic bands) and can be easily implemented long-term in the patient's home-setting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise intervention | Experimental | Home-based, minimal equipment exercise training program. |
|
| Control | No Intervention | Usual care (study participation does not have any impact on regular treatment or treatment decisions, including participation in other exercise training programs or rehabilitation programs) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Behavioral | Home-based exercise training program that requires only minimal equipment, and is individually adaptable to the participant's exercise level (6 times per week; 15-20 min; 38 exercise cards and one interactive training agenda booklet). After randomization, a health care professional (HOMEX coach) will visit the intervention group participants at their home to set up the training location, to instruct the exercises and to establish individualized goals. Follow-up visits are planned after 3 and 8-9 weeks. Regular telephone calls will be conducted by the same HOMEX coach to motivate the patients, to discuss training progress and concrete benefits and barriers, and to adapt goals and the training program. Additional intervention elements are that a relative or friend is involved as a "sparring" partner to support the participant. The general practitioner is informed about the participation of his/her patient in the intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Dyspnea | Dyspnea domain of the Chronic Respiratory Questionnaire (CRQ); 5 questions; 7-point Likert-type scale ranging from 1 (most severe dyspnea) to 7 (no dyspnea) | Change from baseline to 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Dyspnea | Dyspnea domain of the Chronic Respiratory Questionnaire (CRQ); 5 questions; 7-point Likert-type scale ranging from 1 (most severe dyspnea) to 7 (no dyspnea) | Change from baseline to 3, 6 and 12 months |
| Exercise capacity |
| Measure | Description | Time Frame |
|---|---|---|
| Compliance to the exercise training program | Percentage of fulfilled training sessions based on training diaries | Assessed daily by intervention group participants during 12 months |
| Satisfaction with the exercise training program |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinik Barmelweid | Barmelweid | 5017 | Switzerland | |||
| Berner Reha Zentrum AG |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35952766 | Derived | Frei A, Radtke T, Dalla Lana K, Brun P, Sigrist T, Spielmanns M, Beyer S, Riegler TF, Busching G, Spielmanns S, Kunz R, Cerini T, Braun J, Tomonaga Y, Serra-Burriel M, Polhemus A, Puhan MA. Effectiveness of a Long-term Home-Based Exercise Training Program in Patients With COPD After Pulmonary Rehabilitation: A Multicenter Randomized Controlled Trial. Chest. 2022 Dec;162(6):1277-1286. doi: 10.1016/j.chest.2022.07.026. Epub 2022 Aug 8. | |
| 30823913 |
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| ID | Term |
|---|---|
| D002908 | Chronic Disease |
| D008173 | Lung Diseases, Obstructive |
| D012120 | Respiration Disorders |
| D009043 | Motor Activity |
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D008171 | Lung Diseases |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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|
Six-Minute Walk Test (walk distance) and
1-min Sit-to-Stand Test (number of repetitions)
| Change from baseline to 12 months |
| Health-related quality of life | Chronic Respiratory Questionnaires (CRQ): Fatigue, emotional function, mastery domain and EuroQoL (EQ-5D-5L): 5 Dimensions - Mobility, self-care, usual activities, pain/discomfort, anxiety/depression including 1 item each with 5 levels | Change from baseline to 12 months |
| Health status | Visual analogue scale "Feeling thermometer" (0-100 scale; 0= "worst health you can imagine"; 100="best health you can imagine") | Change from baseline to 12 months |
| Exacerbations | Event based, patient reported | During entire study, assessed at 12 months |
| Symptoms | Questionnaire, COPD Assessment Test | Change from baseline to 12 months |
Questionnaire (Likert-Type scales)
| From baseline to 12 months |
| Experience with the exercise training program | Semi-structured interview | From baseline to 12 months (assessed at 12 months) |
| Health professionals' feedback | Semi-structured interview | Assessed at 12 months |
| Cost effectiveness | Questionnaire: cost per quality-adjusted life year | From baseline to 12 months (assessed at 3, 6, 12 months) |
| Heiligenschwendi |
| 3625 |
| Switzerland |
| Zürcher RehaZentren Wald | Wald | 8636 | Switzerland |
| Kantonsspital Winterthur | Winterthur | 8401 | Switzerland |
| University of Zurich | Zurich | 8001 | Switzerland |
| Derived |
| Frei A, Radtke T, Dalla Lana K, Braun J, Muller RM, Puhan MA. Effects of a long-term home-based exercise training programme using minimal equipment vs. usual care in COPD patients: a study protocol for two multicentre randomised controlled trials (HOMEX-1 and HOMEX-2 trials). BMC Pulm Med. 2019 Mar 1;19(1):57. doi: 10.1186/s12890-019-0817-7. |
| D012140 | Respiratory Tract Diseases |
| D001519 | Behavior |