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| ID | Type | Description | Link |
|---|---|---|---|
| 2017-A03012-51 | Other Identifier | ID-RCB number, ANSM |
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Self-administered questionnaire survey to determine the presence or absence of joint pain during bevacizumab treatment for lung, ovarian, colorectal cancers.
The principal end-point is the frequency of arthralgia after 6 months of treatment with Bevacizumab.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | patients with ovarian, colorectal or bronchopulmonary cancer receiving Bevacizumab |
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| Measure | Description | Time Frame |
|---|---|---|
| Frequency of arthralgia | Frequency of joint manifestations of any grade according to the CTCAE (Common Terminology Criteria for Adverse Events) scale version 4.0 observed between the start of bevacizumab treatment and 6 months of treatment. | At 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| correlation between global cancer response and occurrence of arthralgia | baseline, at 3 months, at 6 months | |
| auto questionnaire specific to the study | 16 questions concerning the location, intensity, management of joint pain |
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Inclusion Criteria:
Exclusion Criteria:
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Patients treated with Bevacizumab for Lung, ovarian or colorectal cancers.
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| Name | Affiliation | Role |
|---|---|---|
| Marie-Hélène Viellard, MD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Oscar Lambret | Lille | France | ||||
| Hôpital Huriez. CHRU |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33438069 | Result | Vauleon E, Behal H, Lebellec L, Desbarbieux R, Baldacci S, Simon N, Pannier D, Vieillard MH, Turpin A. Does bevacizumab increase joint pain in patients with cancer? Results of the prospective observational BEVARTHRALGIA study. Cancer Chemother Pharmacol. 2021 Apr;87(4):533-541. doi: 10.1007/s00280-020-04226-6. Epub 2021 Jan 12. |
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| ID | Term |
|---|---|
| D018771 | Arthralgia |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
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| Baseline at 3 months, at 6 months |
| Lille |
| France |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |