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| ID | Type | Description | Link |
|---|---|---|---|
| R21EY027468 | U.S. NIH Grant/Contract | View source |
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Enrollment and other trial activities were halted by COVID-19 pandemic.
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| Name | Class |
|---|---|
| Johns Hopkins University | OTHER |
| National Eye Institute (NEI) | NIH |
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Hemispatial neglect is a disorder where the patient has difficulty attending to objects and information in the left side of space, which occurs following strokes to the right side of the brain. This project is designed to help us understand how optokinetic stimulation treats the symptoms of hemispatial neglect.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Optimization of OKS | Experimental | Crossover study examining various OKS protocols on improving symptoms of hemispatial neglect |
|
| Safety and efficacy study | Experimental | Randomized study assessing the safety and efficacy of OKS in treating hemispatial neglect |
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| Effect of repetitive stimulation | Experimental | Benefits of daily, repetitive OKS in treating hemispatial neglect |
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| OKS and gait | Experimental | Effect of OKS on gait and balance |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OKS | Device | Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Hemispatial neglect scores | Performance on Center of Cancellation Test | After 1 hour of OKS |
| Change in Hemispatial neglect scores | Performance on Behavioral Inattention Test | After 1 hour of OKS |
| Effect of OKS on vision | visual acuity | After 1 hour of OKS |
| Effect of OKS on vision | reading speed | After 1 hour of OKS |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in secondary hemispatial neglect scores | Line bisection score | After 1 hour of OKS |
| Changes in secondary hemispatial neglect scores | grip strength |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chun Lim, MD | Beth Israel Deaconess Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34196963 | Derived | Longley V, Hazelton C, Heal C, Pollock A, Woodward-Nutt K, Mitchell C, Pobric G, Vail A, Bowen A. Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury. Cochrane Database Syst Rev. 2021 Jul 1;7(7):CD003586. doi: 10.1002/14651858.CD003586.pub4. |
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| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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Patient blinded
| After 1 hour of OKS |
| Changes in secondary hemispatial neglect scores | extinction score | After 1 hour of OKS |
| Effect of OKS on gait | Gait assessment | After 1 hour of OKS |
| Effect of OKS on gait | Balance assessments | After 1 hour of OKS |
| D013568 | Pathological Conditions, Signs and Symptoms |