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Keratoconus is a bilateral (but usually asymmetrical) non-inflammatory progressive thinning process of the cornea. It manifests as characteristic cone-like ectasia of the cornea associated with irregular stromal thinning, resulting in a cone-like bulge , which causing irregular astigmatism and vision impairment.
Keratoconus is the most common form of corneal ectasia, with an incidence of 50-230 per 100,000 persons.Pentacam used diagnose & detect the progression in patients with keratoconus and also provide a detailed information about corneal tomography and topography.
In the last few years, it has been shown that in healthy individuals the posterior corneal surface has not only a different amount of astigmatism but also a different alignment of the steep meridian.
The aim of this research is to compare the amount and axis alignment of anterior and posterior corneal astigmatism in keratoconus with a healthy controlled group .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with keratoconus | Active Comparator | Pentacam will be used for comparison between astigmatism in patients with keratoconus and normal people at the same age and sex. |
|
| Normal people at the same age and sex | Placebo Comparator | Pentacam will be used for comparison between astigmatism in patients with keratoconus and normal people at the same age and sex. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pentacam | Device | Pentacam will be used to measure the magnitude and axis orientation of anterior and posterior corneal astigmatism. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Comparison between astigmatism in patients with keratoconus and normal people. | Pentacam will be used for comparison between astigmatism in patients with keratoconus and normal people at the same age and sex | Two years |
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Inclusion Criteria:
Specific diagnostic signs is asymmetric refractive errors with high progressive or irregular astigmatism, and elevated keratometry values, scissoring of the red reflex, Vogt striae, Fleischer rings, inferior or central steepening on topography with abnormal localized steepening .
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9493273 | Background | Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998 Jan-Feb;42(4):297-319. doi: 10.1016/s0039-6257(97)00119-7. |
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| ID | Term |
|---|---|
| D007640 | Keratoconus |
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D005128 | Eye Diseases |
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