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| Name | Class |
|---|---|
| Universität Münster | OTHER |
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The aim of the study is to find out the effects a specific religious fast (i.e. Bahá'à fast) has on certain metabolic parameters, hydration, psyche and circadian clock. In a follow-up questionnaire series in 2019 we want to additionally validate a specific questionnaire for Bahai fasting, which was developed in 2018.
Followers of the Bahá'à Faith worldwide follow a yearly fasting tradition, where they fast intermittently for nineteen days. The intermittent fast is defined as abstinence from any food, drink and smoking from sunrise until sunset. These nineteen days are always in March and so do not coincide with climatic extremes in any country worldwide. This makes this kind of fasting a good model to study the psychological and medical effects of intermittent fasting in humans.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intermittent Fasting | Other | Intermittent Fasting with abstinence from food and drink daily from sunrise to sunset for nineteen consecutive days in March 2018 |
| Measure | Description | Time Frame |
|---|---|---|
| Serum Osmolarity | Measured in subsample of study participants (venous blood sample) osmol/l | 12 hours |
| In 2019: Validation of new questionnaire | New questionnaire, developed in 2018, regarding Bahai fasting | 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Urine Osmolality | Measured in subsample of participants, in spontaneous Urine sample and 12h/24h Urine samples osmol/kg | 24 hours |
| Acid-base balance | Measured in subsample of study participants (venous blood sample) Measured with Radiometer, Base excess (mmol/l) |
| Measure | Description | Time Frame |
|---|---|---|
| Questionnaire: HADS (Hospital Anxiety and Depression Score) | Anxiety and depression | 5 Minutes |
| Systolic and diastolic blood pressure | Measured in subsample of study participants Measured by clinician, mmHg |
Inclusion Criteria:
Exclusion Criteria:
Exclusion Criteria for subsample (energy metabolism measurements and microdialysis)
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Members of the Bahá'à community residing in Germany
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| Name | Affiliation | Role |
|---|---|---|
| Andreas Michalsen, Prof. Dr. | Charité University Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité | Berlin | 14109 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34395487 | Result | Koppold-Liebscher DA, Klatte C, Demmrich S, Schwarz J, Kandil FI, Steckhan N, Ring R, Kessler CS, Jeitler M, Koller B, Ananthasubramaniam B, Eisenmann C, Mahler A, Boschmann M, Kramer A, Michalsen A. Effects of Daytime Dry Fasting on Hydration, Glucose Metabolism and Circadian Phase: A Prospective Exploratory Cohort Study in Baha'i Volunteers. Front Nutr. 2021 Jul 29;8:662310. doi: 10.3389/fnut.2021.662310. eCollection 2021. | |
| 35011024 |
| Label | URL |
|---|---|
| Results publication 1 | View source |
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| ID | Term |
|---|---|
| D015438 | Health Behavior |
| D000093763 | Intermittent Fasting |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D005215 | Fasting |
| D005247 | Feeding Behavior |
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Blood, urine
| 5 Minutes |
| 5 Minutes |
| BMI | Measured in subsample of study participants Quantitative, kg/m2 | 10 Minutes |
| Microdialysis | Measured in subsample of study participants | 3 hours |
| Indirect calorimetry | Measured in subsample of study participants | 2 hours |
| Individual Interview | Measured in subsample of study participants | 30 Minutes, three times during study |
| Activation of clock genes | Measured in subsample of study participants Measured in monocytes | 3 Minutes |
| Result |
| Mahler A, Jahn C, Klug L, Klatte C, Michalsen A, Koppold-Liebscher D, Boschmann M. Metabolic Response to Daytime Dry Fasting in Baha'i Volunteers-Results of a Preliminary Study. Nutrients. 2021 Dec 29;14(1):148. doi: 10.3390/nu14010148. |
| 37878201 | Derived | Steckhan N, Ring R, Borchert F, Koppold DA. Triangulation of Questionnaires, Qualitative Data and Natural Language Processing: A Differential Approach to Religious Baha'i Fasting in Germany. J Relig Health. 2024 Oct;63(5):3360-3373. doi: 10.1007/s10943-023-01929-x. Epub 2023 Oct 25. |