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A retrospective study based on Thai data from Nutrition Day study (nD). Comparing clinical outcome between malnourished patients who were prescribed oral nutrition supplement along with hospital diet and those without oral nutrition supplement.
Prevalence of malnutrition in hospitalized patients varies from 30-70% depend on category of patients recruited. Adverse effects of malnutrition include increase of infection complication, increase hospital length of stay, and increase mortality. Prescription of oral nutrition supplement (ONS) have been proved to provide patients more calorie and protein intake and can improve patients' outcome.
Despite the proved benefits of oral nutrition supplement(ONS), prescription of it in Thai hospitalized patients are far less than it should. The main reason of this under-practice is the limitation of health policies which considered ONS as an optional from main meals. Additional cost for ONS has to be paid by patients themselves, therefore the patients who have no willing to pay usually refuse to receive ONS. Unawareness of physician regarding its benefits is also a problem. In order to convince Thai authorities to allow for reimbursement of ONS and encourage prescription of ONS among physicians, an evidence based benefits of ONS in large Thai population is needed.
The nD study was a single-day, population-based, standardized, multinational, cross-sectional audit and was performed worldwide, includes Thailand, in hospitals, nursing homes and intensive care units performing since 2006 to present. Every year, registered hospitals survey their patients regarding nutritional status, nutritional support. A follow-up for clinical outcome are perform at 30 days after the first survey, include mortality, readmission. This study will based on data of Thai patients collected from nD study during 2006-2016.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| oral nutrition supplement group | hospitalized malnourished patients who were received oral nutrition supplement during hospital course |
| |
| control group | hospitalized malnourished patients who were received only hospital food during hospital course |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| oral nutrition supplement | Other | receiving prescription of oral nutrition supplement during hospitalization |
|
| Measure | Description | Time Frame |
|---|---|---|
| 30-day mortality | dead rate at 30 days after study date will be extracted from hospital medical record by hospital staff | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Discharge rate | Discharge status at 30 day will be extracted from hospital medical record by hospital staff | 30 days |
| Hospital length of stay | Hospital length of stay will be extracted from hospital medical record by hospital staff |
| Measure | Description | Time Frame |
|---|---|---|
| prevalence of oral nutrition supplement prescription in Thai hospitalized patients | prevalence of oral nutrition supplement prescription in Thai hospitalized patients | 10 years |
Inclusion Criteria:
Exclusion Criteria:
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Thai hospitalized patients
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| Name | Affiliation | Role |
|---|---|---|
| Pierre Singer, Professor | Rabin Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rabin medical center | Petah Tikva | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19370584 | Background | Milne AC, Potter J, Vivanti A, Avenell A. Protein and energy supplementation in elderly people at risk from malnutrition. Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD003288. doi: 10.1002/14651858.CD003288.pub3. | |
| 23448109 | Background | Philipson TJ, Snider JT, Lakdawalla DN, Stryckman B, Goldman DP. Impact of oral nutritional supplementation on hospital outcomes. Am J Manag Care. 2013 Feb;19(2):121-8. |
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| ID | Term |
|---|---|
| D044342 | Malnutrition |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| 30 days |
| Re-admission rate | Re-admission rate will be extracted from hospital medical record by hospital staff | 30 days |
| 17964008 | Background | Norman K, Kirchner H, Freudenreich M, Ockenga J, Lochs H, Pirlich M. Three month intervention with protein and energy rich supplements improve muscle function and quality of life in malnourished patients with non-neoplastic gastrointestinal disease--a randomized controlled trial. Clin Nutr. 2008 Feb;27(1):48-56. doi: 10.1016/j.clnu.2007.08.011. Epub 2007 Oct 25. |