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Background:
Fournier's gangrene it's a necrotizing infection of the genital area, with high morbidity and mortality. The site of infection its the origin of the necrotizing fasciitis. There are 4 well known origins of Fournier's gangrene: Testicular, Intestinal, Urinary and cutaneous, and its prognostic value has not been established yet, that's because the lack of case series with adequate number of patients. This is a retrospective study in which we evaluate the prognostic factors of every patient and its mortality compared with its origin area and multiple scores with their survival rates and hospital stay.
Objective:
To evaluate origins of Fournier's gangrene as a prognostic value in the morbidity and mortality.
Patients and methods:
This is a retrospective study where patients from a single hospital from 2007 to 2016 were included. They were categorized in 4 groups matching the origin of infection. In every group categorizing with the origin of infection and determined severity factors, days of hospital stay, Fournier's gangrene severity index and mortality. A statistic analysis will be done using lineal multivariable analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intestinal origin | Either perianal abcess or rectal carcinoma |
| |
| Testicular Origin | Complicated epididymitis with fascitis, |
| |
| Urinary Origin | From urinary tract infection or fistulae from urethral trauma |
| |
| Cutaneous Origin | mostly folliculitis, and skin infections |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aggressive debridement | Procedure | Aggressive debridement of the tissues undergoing fascitis |
|
| Measure | Description | Time Frame |
|---|---|---|
| Fournier's Gangrene Severity Index | A score to predict mortality in this kind of patients | 0-24 hours |
| Hospital stay ( in days) | The patients hospital stay | 0 to 2 months |
| Couture | Positive or negative couture and the bacterias growing in the abscess | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Diabetes mellitus | if the patient had diabetes mellitus type 2 or not | 0 - 100 years |
| Hypertension | if the patient had arterial hypertension or not |
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Inclusion Criteria
Exclusion Criteria
Male patients with Fournier's Gangrene
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Patients from a single hospital (Hospital Universitario "Dr Jose E. Gonzalez") from 2007 to 2016 were included.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Universitario "Dr Jose Eleuterio Gonzalez" | Monterrey | 64460 | Mexico |
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| 0 - 100 years |
| Alcohol drinking | if the patient drinks alcohol or not | 0 - 100 years |
| Tobacco smoking | if the patient smokes or not | 0 - 100 years |
| ID | Term |
|---|---|
| D018934 | Fournier Gangrene |
| D005734 | Gangrene |
| ID | Term |
|---|---|
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D009336 | Necrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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