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| Name | Class |
|---|---|
| Sistema Nacional de Investigadores de Panamá | UNKNOWN |
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To evaluate the duration of labour (active phase of labour) in nulliparous women with gestations between 37 and 41 6/7 weeks when 20 mg of Hyoscine butylbromide was applied intravenously and compared with similar patients that received a placebo.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hyoscine Butylbromide 20Mg/1mL Injection | Experimental | Nulliparous women with gestations at term receive 20 mg of Hyoscine butylbromide IV upon arrival in the Labor and Delivery Unit (4-5 cms). |
|
| Saline solution | Placebo Comparator | Nulliparous women with gestations at term receive Saline Solution IV upon arrival in the Labor and Delivery Unit (4-5 cms). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hyoscine Butylbromide 20Mg/1mL Injection | Drug | Nulliparous women with gestations at term receive 20 mg of Hyoscine butylbromide upon arrival in the Labor and Delivery Unit (4-5 cms). |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of first stage of labor | Time measured from the moment the patient receive the allocated medication/placebo to complete dilation | 24 hours |
| Rate of cervical dilation | Speed of cervical dilation (cms/hour) from the moment the patient receive the allocated medication/placebo to complete dilation | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of labor | Time measured from the moment the patient receive the allocated medication/placebo to delivery | 24 hours |
| Fetal and neonatal complications | Number of adverse events (fetal or neonatal) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Osvaldo Reyes, MD | Maternidad del Hospital Santo Tomás | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saint Thomas Maternity Hospital | Panama City | Panama |
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| ID | Term |
|---|---|
| D002086 | Butylscopolammonium Bromide |
| D007267 | Injections |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D000644 | Quaternary Ammonium Compounds |
| D000588 | Amines |
| D009930 | Organic Chemicals |
| D012602 | Scopolamine Derivatives |
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| Saline Solution | Drug | Nulliparous women with gestations at term receive 20 mg of saline solution upon arrival in the Labor and Delivery Unit (4-5 cms). |
|
| 72 hours |
| D014326 |
| Tropanes |
| D053961 | Azabicyclo Compounds |
| D001372 | Aza Compounds |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D019086 | Bridged Bicyclo Compounds, Heterocyclic |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |