Staying confined in the bed is frequent at the end of life. The cancer patients can also experiment this situation, and consequences are painful, with pain increasing with the time. This pain are related to the joints stiffing , muscles mass decreasing, and tendons retractions . The non pharmacological approach associated with the conventional treatments can be interesting to assess in this frails patients.

Inclusion Criteria:

• Man or woman
• Aged 18 years or older
• Having signed informed consent to participate in the study
• Patient affiliated to a social security scheme
• Patient with pain affecting the musculoskeletal system following prolonged bed rest
• Capable to understand French
• Capable of completing self-assessment scales

Exclusion Criteria:

• Patients with bone metastases at risk for the use of osteopathy
• Patients under legal protection measures
• Patients with cognitive impairment preventing self-evaluation
• Patient who is considered too fragile or with a clinical condition too unstable by the doctor refer to be included in the study
• Patients in the pre-agonic or agonic phase