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Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.
Prospective cohort study. Study approval by local ethics committee. Informed written consent. Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Preterm group | included pregnant females delivered prior to completed 37 weeks of gestation. All participants underwent assessment of uterine artery Doppler indices and maternal serum homocysteine estimation |
| |
| Term group | Included pregnant females delivered after completed 37 weeks of gestation. All participants underwent assessment of uterine artery Doppler indices and maternal serum homocysteine estimation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Uterine artery doppler | Diagnostic Test | Uterine artery Doppler pulsatility indices |
|
| Measure | Description | Time Frame |
|---|---|---|
| The accuracy of serum homocysteine levels and uterine artery pulsatility indices (UtA-PI ) for prediction of preterm labor | Sensitivity (%), specificity (%), positive predictive value (%), negative predictive value (%), positive likelihood ratio (number), negative likelihood ratio (number), accuracy (%) of serum homocysteine and UtA-PI for prediction of preterm labor | Single measurement at the end of the study ( around 37 gestational weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Gestational age at delivery | Gestational age at delivery (Weeks), | Single measurement at the end of the study ( around 37 gestational weeks) |
| Demographic and clinical characteristics of the study groups |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant with singleton pregnancy, more than 28 and less than 35 gestational weeks.
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| ID | Term |
|---|---|
| D007752 | Obstetric Labor, Premature |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| Maternal serum homocysteine estimation | Diagnostic Test |
|
Maternal age (year), Body mass index (kilogram per squared meter), Gestational age at admission (Weeks), Maternal serum Homocysteine level ( micromoles/liter), uterine artery pulsatility index ( number)
| Single measurement on the day one of hospital admission between 28-35 gestational weeks |