Inclusion visit:
- Introduction to the study
- Inclusion in study
- Baseline information is obtained
- Instruct subject to pre-strip of abdominal skin
Test visits 1-25 (up to maximum 25 visits per subject. (1-3 days after pre-stripping the abdominal skin):
- Baseline measurements are conducted on both sides of the stomach (TEWL, hydration, erythema, pH - 3 repeated measurements under each adhesive strip area (upper, middle and bottom of adhesive strip)
- Potential wetting of skin - shower/bicycle exercise (max 60 minutes) and after-wetting baseline measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip))
- Adhesive strips are weighted and applied
- Potential shower/bicycle exercise (max 60 minutes)
- Adhesive strips are removed at pre-defined timeslots (peel force measured)
- Discomfort when strip was peeled of is evaluated by subject (VAS)
- Measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip))
- Acclimatization ½
- Measurements are conducted (TEWL, hydration, erythema, pH - 3 times/strips (upper, middle and bottom of adhesive strip))
- Adhesive strips are weighed
- Photo of adhesive strips
The subjects can be asked to apply and change strips every 24 hours between two test visits but for a maximum of 10 days between two visits. The strips should be applied at the same place every time.