PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients

The PREPARE-MVR Study: PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients

The PREPARE-MVR (PRediction of Early PostoperAtive Right vEntricular failure in Mitral Valve Replacement/Repair patients) Study aims to evaluate those preoperative factors which can predict the early postoperative right ventricular failure or determine the functional shift seen in right ventricular function after mitral valve replacement/repair. The PREPARE-MVR study focuses mainly on echocardiographic (both conventional and advanced) parameters and includes right heart catheterization intraoperatively and in the early postoperative period as gold standard method.

Inclusion Criteria:

• patients admitted for mitral valve replacement/repair
• severe mitral valve insufficiency

Exclusion Criteria:

• preoperative right ventricular dysfunction
• cardiac surgery in medical history
• infective endocarditis
• primary cardiomyopathies
• congenital heart disease
• decreased left ventricular ejection fraction
• pulmonary embolism in medical history
• severe chronic obstructive pulmonary disease
• primary pulmonary hypertension
• any malignancy affecting right heart