Atrial and Ventricular Wall Stress During Breathing | NCT03436030 | Trialant

Atrial and Ventricular Wall Stress During Breathing | NCT03436030 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Single arm, breathing manuevers	Experimental	All subjects perform/undergo Valsalva, Muller, CPAP, hand grip, and passive leg raise, with ultrasound examination of heart recorded before and during the manoeuvre.	Other: Simple breathing manuevers during brief echocardiographic imaging

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Simple breathing manuevers during brief echocardiographic imaging	Other	Valsalva, Muller, light mask CPAP, leg raising, hand grip.	Single arm, breathing manuevers

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Change in atrial wall stress during breathing manoeuver, compared to control measurement immediately before the breathing manoeuver	Echocardiographic measure, comparing control measurement to measurement during breathing manoeuver	30 seconds, i.e. control measurement and then measurement during breathing manoeuver observed from same breathing/measurement sequence

Contacts/Locations Module

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
35354482	Derived	Gottfridsson P, A'Roch R, Lindqvist P, Law L, Myrberg T, Hultin M, A'Roch A, Haney M. Left atrial contraction strain and controlled preload alterations, a study in healthy individuals. Cardiovasc Ultrasound. 2022 Mar 30;20(1):8. doi: 10.1186/s12947-022-00278-1.