Severe PID With Lymphoproliferation and Neutropenia

Phenotype-genotype Correlation in a Sub-population of Severe Primary Immunodeficiency With Lymphoproliferation and Neutropenia

The purpose of this study is to analyse the phenotype in a sub-population of adults with severe primary immunodeficiency with lymphoproliferation and neutropenia and to decipher the possible pathways involved, especially under the hypothesis of a CTLA4/LRBA schema

Inclusion Criteria :

• >18 years old
• CVID (Common Variable Immunodeficiency)
• Neutropenia
• Lymphoproliferation

Exclusion Criteria :

- Secondary immunodeficiency